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Disease

Shoulder Pain

Late-stage therapeutic developmentEmerging research
MeSHShoulder Pain
2
Publications
20
Clinical trials
2026
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 2 clinical trials expected to report results, the earliest in Q3 2026.
  • Active recent publication activity.
Upcoming Milestones
Research Highlights1View
Clinical Milestones5View
Results posted 1
Results expected 2
Recently completed 2
Activity timeline6

Clinical trials

18 sponsors · 1 new · 0 completed in the last 12 months (net +1)

The current development programme across all trial phases.

Clinical programme
20
All trials
6
Active
14
Late-stage
6
Completed
Late-stage studies

Connective Tissue Matrix (CTM) for Rotator Cuff Tendinopathy: A Randomized Controlled Trial

Phase 4 · Active, not recruiting · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Multimodal Nonopioid Pain Protocol Following Shoulder Arthroplasty Surgery

Phase 4 · Active, not recruiting · Henry Ford Health System

Comparative Efficacy of Buprenorphine Transdermal Patch Versus Tramadol in Postoperative Analgesia for Shoulder Arthroscopy: a Randomized Controlled Trial.

Phase 4 · Active, not recruiting · medina medical center

The Effect of Deep Neuromuscular Block and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity in Shoulder Surgery Using a Deltopectoral Approach

Phase 4 · Completed · Universitaire Ziekenhuizen KU Leuven

Interscalene Single Shot With Plain Bupivacaine Versus Liposomal Bupivacaine for Arthroscopic Shoulder Surgery

Phase 4 · Completed · University of Southern California

Preoperative Duloxetine to Prevent Postoperative Shoulder Pain After Gynecological Laparoscopies

Phase 3 · Completed · Assiut University
Recently completed

The Effect of Deep Neuromuscular Block and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity in Shoulder Surgery Using a Deltopectoral Approach

Phase 4 · Completed · Universitaire Ziekenhuizen KU Leuven

Interscalene Single Shot With Plain Bupivacaine Versus Liposomal Bupivacaine for Arthroscopic Shoulder Surgery

Phase 4 · Completed · University of Southern California

Incidence of Flare Reaction Following Shoulder Steroid Injections: Comparison of Depo-medrol (Methylprednisolone) and Kenalog (Triamcinolone)

Phase 4 · Completed · Campbell Clinic

Preoperative Duloxetine to Prevent Postoperative Shoulder Pain After Gynecological Laparoscopies

Phase 3 · Completed · Assiut University

Effect of Parecoxib on the Change of Shoulder Pain Threshold After Gynecological Laparoscopies

Phase 4 · Completed · First Affiliated Hospital, Sun Yat-Sen University

An Exploratory, Randomized, Single Blinded, Placebo-Controlled, Dose-Ranging Study of the Safety and Efficacy of "MILNACIPRAN" in Subjects With Chronic Shoulder Pain

Phase 4 · Completed · Valera Bussell

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20232026
Major themes6
  • Chronic Pain1
  • Electric Stimulation Therapy1
  • Mental Disorders1
  • Shoulder Pain1
  • Sleep Initiation and Maintenance Disorders1
  • Transcutaneous Electric Nerve Stimulation1
Leading journals2
  • American journal of physical medicine & rehabilitation1
  • The journal of headache and pain1
Leading researchers8
  • Aman MM1
  • Boggs JW1
  • Cheng Y1
  • Crosby ND1
  • Fang M1
  • Gutierrez GJ1
  • Huffman WJ1
  • Kong L1
Affiliations (unnormalised)6
  • Research Institute of Tuina1
  • School of Acupuncture-Moxibustion and Tuina1
  • School of Rehabilitation Science1
  • Shepherd Center1
  • Shuguang Hospital1
  • Wayne State University1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Unilateral or bilateral pain of the shoulder. It is often caused by physical activities such as work or sports participation, but may also be pathologic in origin.

Identifiers
MeSHShoulder Pain
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.