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Disease

Surgical Wound Infection

Late-stage therapeutic developmentEmerging research
MeSHSurgical Wound Infection
1
Publications
15
Clinical trials
2011
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

Approval: Ertapenem SUN (EMA)

Regulatory2022-07-15EMA

Health-care-associated infection in Africa: a systematic review.

Research2011-07-20Bulletin of the World Health Organization

Approval: Invanz (EMA)

Regulatory2002-04-18EMA

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 3 clinical trials expected to report results, the earliest in Q3 2026.
Upcoming Milestones
Clinical Milestones4View
Results expected 3
Recently completed 1
Activity timeline4

Clinical trials

15 sponsors · 2 new · 0 completed in the last 12 months (net +2)

The current development programme across all trial phases.

Clinical programme
15
All trials
4
Active
13
Late-stage
6
Completed
Late-stage studies

The Effect of Pre-Operative Bacterial Decolonization on Post-Operative Infection Rate for Lower Extremity Wounds Healing by Second Intention

Phase 3 · Recruiting · The Cooper Health System

PErioperative Respiratory Care and Outcomes for patieNts Undergoing hIgh Risk abdomiNal Surgery: A 2x2 Factorial, International Pragmatic Randomised Controlled Trial Across Low and Middle-income Countries

Phase 3 · Recruiting · University of Birmingham

A Prospective Single-blind Placebo-controlled Trial to Establish the Efficacy and Tolerability of 10% Povidone-Iodine for Nasal S. Aureus and Methicillin Resistant S. Aureus (MRSA) Decolonization Among Patients Undergoing Same-day Surgery

Phase 4 · Completed · Rutgers, The State University of New Jersey

A Randomized, Controlled, Phase 3 Study of Gentamicin-Collagen Sponge in General Surgical Subjects at Higher Risk for Surgical Wound Infection

Phase 3 · Completed · Innocoll

PROTOP: Study of the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Localization Infection in Colorectal Surgery

Phase 4 · Completed · Universitat Internacional de Catalunya

Preoperative Oral Antibiotics and Surgical Site Infections in Colon Surgery Without Mechanical Bowel Preparation. A Prospective, Multicentre, Single Blinded, Randomized Trial (ORALEV Study)

Phase 4 · Completed · Hospital Universitari Vall d'Hebron Research Institute
Recruiting

The Effect of Pre-Operative Bacterial Decolonization on Post-Operative Infection Rate for Lower Extremity Wounds Healing by Second Intention

Phase 3 · Recruiting · The Cooper Health System

A Phase 1 Study to Assess Safety and Tolerability of Amicidin-β Topical Solution in Adult Patients Undergoing Interventional Management of a Surgical or Traumatic Wound Infection

Phase 1 · Recruiting · Macro Biologics, Inc.

PErioperative Respiratory Care and Outcomes for patieNts Undergoing hIgh Risk abdomiNal Surgery: A 2x2 Factorial, International Pragmatic Randomised Controlled Trial Across Low and Middle-income Countries

Phase 3 · Recruiting · University of Birmingham

Evaluation of Non-Thermal Plasma as an Innovative Strategy for Optimizing Post-Surgical Wound Treatment in Patients of Thyroid Surgery: An Ethical and Clinical Approach

N/A · Recruiting · National Institute of Nuclear Research - Mexico
Recently completed

A Prospective Single-blind Placebo-controlled Trial to Establish the Efficacy and Tolerability of 10% Povidone-Iodine for Nasal S. Aureus and Methicillin Resistant S. Aureus (MRSA) Decolonization Among Patients Undergoing Same-day Surgery

Phase 4 · Completed · Rutgers, The State University of New Jersey

PROTOP: Study of the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Localization Infection in Colorectal Surgery

Phase 4 · Completed · Universitat Internacional de Catalunya

Antibiotic Prophylaxis for Revision, Clean Head and Neck Surgery

Phase 4 · Completed · Rabin Medical Center

Preoperative Oral Antibiotics and Surgical Site Infections in Colon Surgery Without Mechanical Bowel Preparation. A Prospective, Multicentre, Single Blinded, Randomized Trial (ORALEV Study)

Phase 4 · Completed · Hospital Universitari Vall d'Hebron Research Institute

Antibiotic Prophylaxis to Prevent Wound Infections Following Implant Removal

Phase 4 · Completed · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

A Randomized, Controlled, Phase 3 Study of Gentamicin-Collagen Sponge in General Surgical Subjects at Higher Risk for Surgical Wound Infection

Phase 3 · Completed · Innocoll

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

Health-care-associated infection in Africa: a systematic review.

Bulletin of the World Health Organization · 2011 · 266 cites
Recent publications

Health-care-associated infection in Africa: a systematic review.

Bulletin of the World Health Organization · 2011 · 266 cites
Leading journals1
  • Bulletin of the World Health Organization1
Leading researchers5
  • Allegranzi B1
  • Bagheri Nejad S1
  • Ellis B1
  • Pittet D1
  • Syed SB1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Infection occurring at the site of a surgical incision.

Identifiers
MeSHSurgical Wound Infection
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.