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Disease

Surgical Wound Infection

Late-stage therapeutic developmentEmerging research
MeSHSurgical Wound Infection
1
Publications
15
Clinical trials
2011
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

Suprafascial Vancomycin Powder for Prevention of Surgical Site Infections After Instrumented Posterior Spinal Fusion

Clinical trial2026-08-05Status changed to Completed · ClinicalTrials.gov

Approval: Ertapenem SUN (EMA)

Regulatory2022-07-15EMA

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 2 clinical trials expected to report results, the earliest in Q3 2026.
Upcoming Milestones
Clinical Milestones3View
Results expected 2
Recently completed 1
Activity timeline3

Clinical trials

15 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
15
All trials
4
Active
13
Late-stage
6
Completed
Late-stage studies

The Effect of Pre-Operative Bacterial Decolonization on Post-Operative Infection Rate for Lower Extremity Wounds Healing by Second Intention

Phase 3 · Recruiting · The Cooper Health System

PErioperative Respiratory Care and Outcomes for patieNts Undergoing hIgh Risk abdomiNal Surgery: A 2x2 Factorial, International Pragmatic Randomised Controlled Trial Across Low and Middle-income Countries

Phase 3 · Recruiting · University of Birmingham

A Prospective Single-blind Placebo-controlled Trial to Establish the Efficacy and Tolerability of 10% Povidone-Iodine for Nasal S. Aureus and Methicillin Resistant S. Aureus (MRSA) Decolonization Among Patients Undergoing Same-day Surgery

Phase 4 · Completed · Rutgers, The State University of New Jersey

A Randomized, Controlled, Phase 3 Study of Gentamicin-Collagen Sponge in General Surgical Subjects at Higher Risk for Surgical Wound Infection

Phase 3 · Completed · Innocoll

PROTOP: Study of the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Localization Infection in Colorectal Surgery

Phase 4 · Completed · Universitat Internacional de Catalunya

Preoperative Oral Antibiotics and Surgical Site Infections in Colon Surgery Without Mechanical Bowel Preparation. A Prospective, Multicentre, Single Blinded, Randomized Trial (ORALEV Study)

Phase 4 · Completed · Hospital Universitari Vall d'Hebron Research Institute
Recruiting

The Effect of Pre-Operative Bacterial Decolonization on Post-Operative Infection Rate for Lower Extremity Wounds Healing by Second Intention

Phase 3 · Recruiting · The Cooper Health System

A Phase 1 Study to Assess Safety and Tolerability of Amicidin-β Topical Solution in Adult Patients Undergoing Interventional Management of a Surgical or Traumatic Wound Infection

Phase 1 · Recruiting · Macro Biologics, Inc.

PErioperative Respiratory Care and Outcomes for patieNts Undergoing hIgh Risk abdomiNal Surgery: A 2x2 Factorial, International Pragmatic Randomised Controlled Trial Across Low and Middle-income Countries

Phase 3 · Recruiting · University of Birmingham

Evaluation of Non-Thermal Plasma as an Innovative Strategy for Optimizing Post-Surgical Wound Treatment in Patients of Thyroid Surgery: An Ethical and Clinical Approach

N/A · Recruiting · National Institute of Nuclear Research - Mexico
Recently completed

A Prospective Single-blind Placebo-controlled Trial to Establish the Efficacy and Tolerability of 10% Povidone-Iodine for Nasal S. Aureus and Methicillin Resistant S. Aureus (MRSA) Decolonization Among Patients Undergoing Same-day Surgery

Phase 4 · Completed · Rutgers, The State University of New Jersey

PROTOP: Study of the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Localization Infection in Colorectal Surgery

Phase 4 · Completed · Universitat Internacional de Catalunya

Antibiotic Prophylaxis for Revision, Clean Head and Neck Surgery

Phase 4 · Completed · Rabin Medical Center

Preoperative Oral Antibiotics and Surgical Site Infections in Colon Surgery Without Mechanical Bowel Preparation. A Prospective, Multicentre, Single Blinded, Randomized Trial (ORALEV Study)

Phase 4 · Completed · Hospital Universitari Vall d'Hebron Research Institute

Antibiotic Prophylaxis to Prevent Wound Infections Following Implant Removal

Phase 4 · Completed · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

A Randomized, Controlled, Phase 3 Study of Gentamicin-Collagen Sponge in General Surgical Subjects at Higher Risk for Surgical Wound Infection

Phase 3 · Completed · Innocoll

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

Health-care-associated infection in Africa: a systematic review.

Bulletin of the World Health Organization · 2011 · 266 cites
Recent publications

Health-care-associated infection in Africa: a systematic review.

Bulletin of the World Health Organization · 2011 · 266 cites
Leading journals1
  • Bulletin of the World Health Organization1
Leading researchers5
  • Allegranzi B1
  • Bagheri Nejad S1
  • Ellis B1
  • Pittet D1
  • Syed SB1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Infection occurring at the site of a surgical incision.

Identifiers
MeSHSurgical Wound Infection
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.