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Disease

Tachycardia

Late-stage therapeutic developmentEmerging research
MeSHTachycardia
2
Publications
20
Clinical trials
2024
Latest publication
Latest activity
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Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Moderate
Key developments
  • 4 clinical trials expected to report results, the earliest in Q4 2026.
Upcoming Milestones
Major developments
Upcoming trial readoutHigh impact
Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm
Results expected Q2 20272026-07-07
Upcoming trial readoutHigh impact
COMparison of Adenosine Versus Diltiazem FOR Supraventricular Tachycardia in the ED (COMFORT-ED) - Pilot Trial
Results expected Q3 20272026-05-28
Clinical Milestones8View
Results posted 1
Results expected 4
Recently completed 3
Activity timeline8

Clinical trials

13 sponsors · 0 new · 4 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
20
All trials
6
Active
16
Late-stage
6
Completed
Late-stage studies

COMparison of Adenosine Versus Diltiazem FOR Supraventricular Tachycardia in the ED (COMFORT-ED) - Pilot Trial

Phase 4 · Recruiting · Anne E. Zepeski

Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm

Phase 3 · Recruiting · Ottawa Heart Institute Research Corporation

Atrial Tachycardia Reduction With Intravenous Use of Magnesium (ATRIUM) Study: Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR

Phase 3 · Recruiting · Wake Forest University Health Sciences

Comparison of Verapamil With Adenosine After Vagal Maneuvers in Patients Presenting With Paroxysmal Supraventricular Tachycardia (pSVT), in a Tertiary Care Hospital of Lahore, Pakistan

Phase 3 · Recruiting · Rashid Latif Medical College

An Open Label Extension Study of Etripamil Nasal Spray in Patients With Paroxysmal Supraventricular Tachycardia

Phase 3 · Completed · Milestone Pharmaceuticals Inc.

Comparison of Single-syringe vs. Double-syringe Techniques for Adenosine Administration in Supraventricular Tachycardia: A Randomized Clinical Trial

Phase 4 · Completed · Hormozgan University of Medical Sciences
Recruiting

COMparison of Adenosine Versus Diltiazem FOR Supraventricular Tachycardia in the ED (COMFORT-ED) - Pilot Trial

Phase 4 · Recruiting · Anne E. Zepeski

Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm

Phase 3 · Recruiting · Ottawa Heart Institute Research Corporation

Atrial Tachycardia Reduction With Intravenous Use of Magnesium (ATRIUM) Study: Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR

Phase 3 · Recruiting · Wake Forest University Health Sciences

Mechanism of Glucose-dependent Insulinotropic Polypeptide (GIP) on Splanchnic Venous Capacitance in Postural Tachycardia Syndrome

Phase 2 · Recruiting · Vanderbilt University Medical Center

The NODE-202 Study Multi-Center, Multi-National, Open-Label, Efficacy and Safety Study of Etripamil Nasal Spray in Pediatric Patients With Paroxysmal Supraventricular Tachycardia

Phase 2 · Recruiting · Milestone Pharmaceuticals Inc.

Comparison of Verapamil With Adenosine After Vagal Maneuvers in Patients Presenting With Paroxysmal Supraventricular Tachycardia (pSVT), in a Tertiary Care Hospital of Lahore, Pakistan

Phase 3 · Recruiting · Rashid Latif Medical College
Recently completed

An Open Label Extension Study of Etripamil Nasal Spray in Patients With Paroxysmal Supraventricular Tachycardia

Phase 3 · Completed · Milestone Pharmaceuticals Inc.

Comparison of Single-syringe vs. Double-syringe Techniques for Adenosine Administration in Supraventricular Tachycardia: A Randomized Clinical Trial

Phase 4 · Completed · Hormozgan University of Medical Sciences

Intravenous Adenosine Versus Diltiazem After Failed Modified Valsalva for Hemodynamically Stable ANVRT in the Emergency Department

Phase 4 · Completed · Haseki Training and Research Hospital

A Randomized Controlled Trial of RyR2 Inhibition With Dantrolene and Susceptibility to Ventricular Arrhythmias in Patients With Structural Heart Disease.

Phase 2/3 · Completed · Vanderbilt University Medical Center

Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Efficacy and Safety Study of Etripamil Nasal Spray Self-Administration for the Termination of Spontaneous Episodes of Paroxysmal Supraventricular Tachycardia in Chinese Patients

Phase 3 · Completed · Corxel Pharmaceuticals

FAST RCT: Prospective Randomized Clinical Trial of Fetal Atrial Flutter & Supraventricular Tachycardia Therapy

Phase 3 · Completed · Edgar Jaeggi

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20212024
Major themes4
  • American Heart Association1
  • Arrhythmias, Cardiac1
  • Catheter Ablation1
  • Cryosurgery1
Leading journals2
  • Circulation1
  • The New England journal of medicine1
Leading researchers8
  • Amit G1
  • Andrade JG1
  • Angaran P1
  • Batra AS1
  • Bennett M1
  • Borquez A1
  • Champagne J1
  • Cuneo B1
Affiliations (unnormalised)1
  • From Vancouver General Hospital (J.G.A.1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.

Identifiers
MeSHTachycardia
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.