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Disease

Takotsubo Cardiomyopathy

Active therapeutic pipelineEmerging research
MeSHTakotsubo Cardiomyopathy
1
Publications
5
Clinical trials
5
Associated genes
2023
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

The Immunology of Takotsubo Syndrome.

Research2023-10-06Frontiers in immunology

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 2 clinical trials expected to report results, the earliest in Q1 2027.
Upcoming Milestones
Major developments
Upcoming trial readoutImportant
Cyclosporine In Takotsubo Syndrome (CIT) Trial
Results expected Q1 20272026-05-01
Upcoming trial readoutImportant
Manganese-enhanced Magnetic Resonance Imaging in Takotsubo Cardiomyopathy
Results expected Q3 20282026-03-24
Clinical Milestones2View
Results expected 2
Activity timeline2

Clinical trials

4 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
5
All trials
2
Active
0
Late-stage
1
Completed
Recruiting

Cyclosporine In Takotsubo Syndrome (CIT) Trial

Phase 2 · Recruiting · University Hospital Heidelberg

Manganese-enhanced Magnetic Resonance Imaging in Takotsubo Cardiomyopathy

N/A · Recruiting · University of Edinburgh
Recently completed

Vacular Structure, Function and Sympathetic Activity in Takotsubo Syndrome

Phase 1/2 · Completed · Danderyd Hospital

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

The Immunology of Takotsubo Syndrome.

Frontiers in immunology · 2023 · 5 cites
Recent publications

The Immunology of Takotsubo Syndrome.

Frontiers in immunology · 2023 · 5 cites
Major themes1
  • Takotsubo Cardiomyopathy1
Leading journals1
  • Frontiers in immunology1
Leading researchers4
  • Hayashi T1
  • Kenzaka T1
  • Lim KRQ1
  • Mann DL1
Affiliations (unnormalised)3
  • Center for Cardiovascular Research1
  • Hyogo Prefectural Tamba Medical Center1
  • Kobe University Graduate School of Medicine1

Associated genes

5 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

VSIG80.05FASTKD50.04KEL0.04DCUN1D20.00ZNF5010.00

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

A transient left ventricular apical dysfunction or ballooning accompanied by electrocardiographic (ECG) T wave inversions. This abnormality is associated with high levels of CATECHOLAMINES, either administered or endogenously secreted from a tumor or during extreme stress.

Identifiers
MeSHTakotsubo Cardiomyopathy
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.