Temporomandibular Joint Disorders
Recent clinical, regulatory, research and industry developments relating to this disease.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 2 clinical trials with recent milestones.
Clinical MilestonesViewHide
- 2026-09-15A Combined Treatment of Manual Therapy and Nervous Vagus Stimulation Versus a Treatment of Manual Therapy Isolated in Patients With Myogenic Temporomandibular DisordersPrimary completion
- 2026-02-01Comparative Study Between the Effectiveness of High Versus Low Molecular Weight Hyaluronic Acid in TMJ ArthrocentesisPrimary completion
- 2026-09-15ClinicalA Combined Treatment of Manual Therapy and Nervous Vagus Stimulation Versus a Treatment of Manual Therapy Isolated in Patients With Myogenic Temporomandibular DisordersPrimary completion
- 2026-02-01ClinicalComparative Study Between the Effectiveness of High Versus Low Molecular Weight Hyaluronic Acid in TMJ ArthrocentesisPrimary completion
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes2
- Sleep Quality1
- Temporomandibular Joint Disorders1
Leading journals1
- Dental and medical problems1
Leading researchers8
- Bombała W1
- Jenča A1
- Orzeszek SM1
- Osiewicz M1
- Paradowska-Stolarz A1
- Seweryn P1
- Waliszewska-Prosół M1
- Więckiewicz M1
Affiliations (unnormalised)5
- Dental Institute1
- Pavol Jozef Šafárik University in Košice and Akadémia Košice1
- Statistical Analysis Center1
- The Maurice and Gabriela Goldschleger School of Dental Medicine1
- Wroclaw Medical University1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Disease biology
Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.
Reference
Authoritative identity, definition & identifiers.
A variety of conditions affecting the anatomic and functional characteristics of the temporomandibular joint. Factors contributing to the complexity of temporomandibular diseases are its relation to dentition and mastication and the symptomatic effects in other areas which account for referred pain to the joint and the difficulties in applying traditional diagnostic procedures to temporomandibular joint pathology where tissue is rarely obtained and x-rays are often inadequate or nonspecific. Common diseases are developmental abnormalities, trauma, subluxation, luxation, arthritis, and neoplasia. (From Thoma's Oral Pathology, 6th ed, pp577-600)
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.