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Disease

Testicular Neoplasms

Late-stage therapeutic developmentEmerging researchSteady momentum
MeSHTesticular Neoplasms
4
Publications
8
Clinical trials
2024
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

Adolescent and Young Adult Germ Cell Tumors: Epidemiology, Genomics, Treatment, and Survivorship.

Research2023-10-11Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Metastatic Testicular Cancer Patterns and Predictors: A Contemporary Population-based SEER Analysis.

Research2023-07-17Urology

Testicular Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.

Research2019-12-01Journal of the National Comprehensive Cancer Network : JNCCN

Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects.

Research2001-05-01Human reproduction (Oxford, England)

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q2 2027.
Upcoming Milestones
Clinical Milestones1View
Results expected 1
Activity timeline1

Clinical trials

8 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
8
All trials
1
Active
1
Late-stage
5
Completed
Recently completed

Phase II Study of Avelumab in Multiple Relapsed/Refractory Testicular Germ Cell Cancer.

Phase 2 · Completed · National Cancer Institute, Slovakia

GAMEC-SHORT (S) & GAMEC-ANTHRACYCLINE(A) (Combination Chemotherapy With GCSF, Actinomycin-D, Methotrexate, Etoposide and Cisplatin) Risk-adapted Protocol for Relapsed Germ Cell Tumours (GCT)

Phase 2 · Completed · Queen Mary University of London

Sequential High-Dose Chemotherapy Combining Two Mobilization and Cyto-Reductive Treatments Followed by Three High-Dose Chemotherapy Regimens Supported by Autologous Stem Cell Transplantation

Phase 2 · Completed · Assistance Publique - Hôpitaux de Paris

Randomized Phase 2 Study of Conventional Dose Chemotherapy Versus High Dose Sequential Chemotherapy as First-line Therapy for Metastatic Poor Prognosis Germ Cell Tumors

Phase 2 · Completed · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Feasibility Study of Interleukin 1-Alpha With Ifosfamide, CBDCA, and Etoposide With Autologous Bone Marrow Transplant in Metastatic Carcinoma and Lymphoma

Phase 1 · Completed · National Cancer Institute (NCI)

Research activity

4 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20012024
Most influential

Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects.

Human reproduction (Oxford, England) · 2001 · 1,444 cites

Testicular Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.

Journal of the National Comprehensive Cancer Network : JNCCN · 2019 · 199 cites

Adolescent and Young Adult Germ Cell Tumors: Epidemiology, Genomics, Treatment, and Survivorship.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024 · 17 cites

Metastatic Testicular Cancer Patterns and Predictors: A Contemporary Population-based SEER Analysis.

Urology · 2023 · 9 cites
Recent publications

Adolescent and Young Adult Germ Cell Tumors: Epidemiology, Genomics, Treatment, and Survivorship.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024 · 17 cites

Metastatic Testicular Cancer Patterns and Predictors: A Contemporary Population-based SEER Analysis.

Urology · 2023 · 9 cites

Testicular Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.

Journal of the National Comprehensive Cancer Network : JNCCN · 2019 · 199 cites

Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects.

Human reproduction (Oxford, England) · 2001 · 1,444 cites
Major themes4
  • Testicular Neoplasms2
  • Environmental Exposure1
  • Lung Neoplasms1
  • Neoplasms, Germ Cell and Embryonal1
Leading journals4
  • Human reproduction (Oxford, England)1
  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology1
  • Journal of the National Comprehensive Cancer Network : JNCCN1
  • Urology1
Leading researchers8
  • Feldman DR2
  • Aggarwal R1
  • Chandrasekar T1
  • Chism D1
  • Cost N1
  • Daneshmand S1
  • Derweesh IH1
  • Emamekhoo H1
Affiliations (unnormalised)6
  • 10Stanford Cancer Institute.1
  • 11Fred & Pamela Buffett Cancer Center.1
  • 12Roswell Park Cancer Institute.1
  • 13Duke Cancer Institute.1
  • 14Huntsman Cancer Institute at the University of Utah.1
  • 15Dana-Farber/Brigham and Women's Cancer Center.1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.

Identifiers
MeSHTesticular Neoplasms
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.