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Disease

Tonsillitis

Late-stage therapeutic developmentEmerging research
MeSHTonsillitis
1
Publications
18
Clinical trials
2022
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q4 2028.
Upcoming Milestones
Clinical Milestones4View
Results expected 1
Recently completed 3
Activity timeline4

Clinical trials

16 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
18
All trials
6
Active
13
Late-stage
6
Completed
Late-stage studies

Bacteriophage Therapy in Acute Tonsillitis

Phase 3 · Active, not recruiting · Tashkent State Medical University (Tashkent Pediatric Medical Institute), Uzbekistan

A Randomized Controlled Clinical Trial of Streptococcus Group A-negative Acute Tonsillitis in Primary Health Care - a Comparison of Phenoxymethylpenicillin and No Antibiotic Treatment

Phase 4 · Recruiting · Katarina Hedin

Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy/Adenoidectomy: Randomized Control Trial

Phase 4 · Recruiting · Children's Healthcare of Atlanta

Single-Dose Intraoperative Methadone for Pain Management in Pediatric Tonsillectomy: A Randomized Double Blind Clinical Trial

Phase 4 · Recruiting · Duke University

A Randomized Controlled Study of 5 and 10 Days Treatment With Phenoxymethylpenicillin for Pharyngotonsillitis Caused by Streptococcus Group A

Phase 4 · Completed · Ass. Prof. Katarina Hedin

Comparison of Treatment Satisfaction and Treatment Adherence of a Novel Application Form "Dose Sipping Technology" (DST) of Oral Clarithromycin vs. Clarithromycin Syrup in Children Suffering From Acute Otitis Media, Tonsillitis, Pharyngitis, or Acute Bacterial Bronchitis (DoSe iT)

Phase 3 · Completed · Grünenthal GmbH
Recruiting

A Randomized Controlled Clinical Trial of Streptococcus Group A-negative Acute Tonsillitis in Primary Health Care - a Comparison of Phenoxymethylpenicillin and No Antibiotic Treatment

Phase 4 · Recruiting · Katarina Hedin

Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy/Adenoidectomy: Randomized Control Trial

Phase 4 · Recruiting · Children's Healthcare of Atlanta

The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain: A Prospective Randomized Controlled Study.

N/A · Recruiting · Ain Shams University

Single-Dose Intraoperative Methadone for Pain Management in Pediatric Tonsillectomy: A Randomized Double Blind Clinical Trial

Phase 4 · Recruiting · Duke University
Recently completed

A Randomized Controlled Study of 5 and 10 Days Treatment With Phenoxymethylpenicillin for Pharyngotonsillitis Caused by Streptococcus Group A

Phase 4 · Completed · Ass. Prof. Katarina Hedin

Analgesic Effect of Single Dose Intravenous Acetaminophen in Pediatric Patients Undergoing Tonsillectomy

Phase 2 · Completed · Nationwide Children's Hospital

Efficacy of IV vs Oral Administration of Acetaminophen for Pain Control Following Tonsillectomy With or Without Adenoidectomy

Phase 4 · Completed · Kaveh Aslani, MD

A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing Tonsillectomy

Phase 4 · Completed · Children's Hospitals and Clinics of Minnesota

Comparison of Treatment Satisfaction and Treatment Adherence of a Novel Application Form "Dose Sipping Technology" (DST) of Oral Clarithromycin vs. Clarithromycin Syrup in Children Suffering From Acute Otitis Media, Tonsillitis, Pharyngitis, or Acute Bacterial Bronchitis (DoSe iT)

Phase 3 · Completed · Grünenthal GmbH

A Multicenter, Randomized, Double-Blind, Double-Dummy Comparative Trial of Azithromycin SR Versus Three-Day Azithromycin for the Treatment of Group A β-Hemolytic Streptococcal Pharyngitis/Tonsillitis in Adolescents and Adults

Phase 3 · Completed · Pfizer

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Major themes7
  • HIV Infections1
  • Mpox, Monkeypox1
  • Proctitis1
  • Sexual and Gender Minorities1
  • Sexually Transmitted Diseases1
  • Smallpox1
  • Tonsillitis1
Leading journals1
  • Lancet (London, England)1
Leading researchers8
  • Acosta-Velásquez KS1
  • Agud-Dios M1
  • Alemany A1
  • Antón A1
  • Arando M1
  • Arroyo-Andrés J1
  • Cabrera JM1
  • Calderón-Lozano L1
Affiliations (unnormalised)6
  • Clinical Laboratory North Metropolitan Area1
  • Clinical Research Department1
  • Hospital Universitari Vall d'Hebron1
  • Hospital Universitario 12 de Octubre1
  • Hospital Universitario La Paz1
  • University Hospital Germans Trias i Pujol1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Inflammation of the tonsils, especially the PALATINE TONSILS but the ADENOIDS (pharyngeal tonsils) and lingual tonsils may also be involved. Tonsillitis usually is caused by bacterial infection. Tonsillitis may be acute, chronic, or recurrent.

Identifiers
MeSHTonsillitis
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.