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Disease

Toxoplasmosis

Late-stage therapeutic developmentEmerging research
MeSHToxoplasmosis
1
Publications
9
Clinical trials
1
Associated genes
2014
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

7 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
9
All trials
2
Active
4
Late-stage
6
Completed
Recruiting

Phase IV Randomized Study of Pyrimethamine, Sulfadiazine, and Leucovorin Calcium for Congenital Toxoplasmosis

Phase 4 · Recruiting · National Institute of Allergy and Infectious Diseases (NIAID)

Adjunctive Dexamethasone for Cerebral Toxoplasmosis: a Double-blinded Randomized Controlled Trial

Phase 2 · Recruiting · Universitas Padjadjaran
Recently completed

Pilot Trial of Valproate as Adjunctive Treatment for Toxoplasma Gondii

Phase 4 · Completed · University of Pittsburgh

Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis

N/A · Completed · University Hospital, Grenoble

Multicenter, Randomized Clinical Trial to Compare the Efficacy and Tolerance of Prenatal Therapy With Pyrimethamine + Sulfadiazine vs Spiramycine to Reduce Vertical Transmission of Toxoplasma Gondii Following Primary Infection in Pregnancy

Phase 3 · Completed · Assistance Publique - Hôpitaux de Paris

Influence of Trimethoprim-sulfamethoxazole for the Recurrence of Retinochoroiditis Toxoplasma Gondii

Phase 3 · Completed · University of Campinas, Brazil

Phase II Randomized Open-Label Trial of Atovaquone Plus Pyrimethamine and Atovaquone Plus Sulfadiazine for the Treatment of Acute Toxoplasmic Encephalitis

Phase 2 · Completed · National Institute of Allergy and Infectious Diseases (NIAID)

Primary Prophylaxis of Cerebral Toxoplasmosis in HIV-Infected Patients

Phase 2 · Completed · National Institute of Allergy and Infectious Diseases (NIAID)

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Major themes1
  • Internationality1
Leading journals1
  • PloS one1
Leading researchers4
  • Flegr J1
  • Israili ZH1
  • Prandota J1
  • Sovičková M1
Affiliations (unnormalised)3
  • Charles University in Prague1
  • Emory University School of Medicine1
  • Wroclaw Medical University1

Associated genes

1 match

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

SDE20.09

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

The acquired form of infection by Toxoplasma gondii in animals and man.

Identifiers
MeSHToxoplasmosis
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.