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Disease

Trachoma

Late-stage therapeutic developmentEmerging research
MeSHTrachoma
2
Publications
11
Clinical trials
2024
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

Control, elimination, and eradication efforts for neglected tropical diseases in the World Health Organization African region over the last 30 years: A scoping review.

Research2024-01-22International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

Trachoma.

Research2022-05-26Nature reviews. Disease primers

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q1 2027.
Upcoming Milestones
Major developments
Major trial resultsHigh impact
Azithromycin Reduction to Reach Elimination of Trachoma
Results posted2026-03-25
Trial discontinuedImportant
Azithromycin Reduction to Reach Elimination of Trachoma B
Withdrawn2029-08-31
Clinical Milestones4View
Results posted 1
Results expected 1
Other updates 2
Activity timeline4

Clinical trials

5 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
11
All trials
1
Active
9
Late-stage
6
Completed
Late-stage studies

Kebele Elimination of Trachoma for Ocular Health

Phase 4 · Active, not recruiting · University of California, San Francisco

Sanitation, Water, and Instruction in Face-washing for Trachoma I/II

Phase 3 · Completed · University of California, San Francisco

Enhancing the A in SAFE: Accelerating Trachoma Elimination in the Republic of South Sudan

Phase 4 · Completed · Emory University

Safety of the Co-administration of Azithromycin, Albendazole and Ivermectin Versus Standard Treatment Regimens During Mass Drug Administration (MDA) in Ethiopia: a Cluster-randomized Trial

Phase 4 · Completed · London School of Hygiene and Tropical Medicine

A Cluster Randomised Trial of the Safety of Co-Administration of IDA (Ivermectin, Diethylcarbamazine and Albendazole) & Azithromycin for Integrated Treatment of Neglected Tropical Diseases

Phase 3 · Completed · Lihir Medical Centre

Azithromycin Reduction to Reach Elimination of Trachoma

Phase 4 · Completed · University of California, San Francisco
Recently completed

Sanitation, Water, and Instruction in Face-washing for Trachoma I/II

Phase 3 · Completed · University of California, San Francisco

Azithromycin Reduction to Reach Elimination of Trachoma

Phase 4 · Completed · University of California, San Francisco

Enhancing the A in SAFE: Accelerating Trachoma Elimination in the Republic of South Sudan

Phase 4 · Completed · Emory University

Safety of the Co-administration of Azithromycin, Albendazole and Ivermectin Versus Standard Treatment Regimens During Mass Drug Administration (MDA) in Ethiopia: a Cluster-randomized Trial

Phase 4 · Completed · London School of Hygiene and Tropical Medicine

A Cluster Randomised Trial of the Safety of Co-Administration of IDA (Ivermectin, Diethylcarbamazine and Albendazole) & Azithromycin for Integrated Treatment of Neglected Tropical Diseases

Phase 3 · Completed · Lihir Medical Centre

Fluorometholone 0.1% as Perioperative Adjunct Therapy for Lid-rotation Surgery in Trachomatous Entropion and Trichiasis, Dose-varying Study

N/A · Completed · University of Pennsylvania

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20222024
Most influential

Trachoma.

Nature reviews. Disease primers · 2022 · 118 cites

Control, elimination, and eradication efforts for neglected tropical diseases in the World Health Organization African region over the last 30 years: A scoping review.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024 · 12 cites
Recent publications

Control, elimination, and eradication efforts for neglected tropical diseases in the World Health Organization African region over the last 30 years: A scoping review.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024 · 12 cites

Trachoma.

Nature reviews. Disease primers · 2022 · 118 cites
Major themes7
  • Disease Eradication1
  • Gonorrhea1
  • Neglected Diseases1
  • Trachoma1
  • Trichiasis1
  • Tropical Medicine1
  • World Health Organization1
Leading journals2
  • International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases1
  • Nature reviews. Disease primers1
Leading researchers8
  • Achu D1
  • Barry A1
  • Burton MJ1
  • Campos A1
  • Farham B1
  • Gower EW1
  • Harding-Esch EM1
  • Impouma B1
Affiliations (unnormalised)6
  • Clinical Research Department1
  • Congo; University of South Florida College of Public Health1
  • Francis I Proctor Foundation1
  • Gillings School of Global Public Health1
  • International Centre for Eye Health1
  • Melbourne School of Population Health1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

A chronic infection of the CONJUNCTIVA and CORNEA caused by CHLAMYDIA TRACHOMATIS.

Identifiers
MeSHTrachoma
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.