Urinary Incontinence, Urge
Recent clinical, regulatory, research and industry developments relating to this disease.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 1 clinical trial expected to report results, the earliest in Q2 2027.
- Active recent publication activity, including 1 notable finding.
Research HighlightsViewHide
Clinical MilestonesViewHide
- 2026-02-25Intradetrusor Botulinum Toxin A for OAB Via 1 Versus 10 Injections: A Randomized Clinical TrialResults posted
- 2026-03-06Cognitive, Urinary, and Functional Trajectories of Older Women Using Pharmacologic Treatment Strategies for Urgency IncontinenceResults expected Q2 2027
- 2026-09-15Efficacy, Neural Repair Mechanism, and Health Economics of a Multimodal Treat-to-Target Strategy Incorporating Vitamin D for Pediatric Overactive Bladder-Wet: A Randomized Controlled TrialPrimary completion
- 2026-06-01Telerehabilitation Versus Supervised Pelvic Floor Muscle Training in Postmenopausal Women With Urinary IncontinencePrimary completion
- 2026-09-15ClinicalEfficacy, Neural Repair Mechanism, and Health Economics of a Multimodal Treat-to-Target Strategy Incorporating Vitamin D for Pediatric Overactive Bladder-Wet: A Randomized Controlled TrialPrimary completion
- 2026-06-01ClinicalTelerehabilitation Versus Supervised Pelvic Floor Muscle Training in Postmenopausal Women With Urinary IncontinencePrimary completion
- 2026-04-15ResearchWireless electrostimulation implants enable sphincter neuromuscular improvement toward mixed urinary incontinence.Zheng T · 2026
- 2026-03-06ClinicalCognitive, Urinary, and Functional Trajectories of Older Women Using Pharmacologic Treatment Strategies for Urgency IncontinenceResults expected Q2 2027
- 2026-02-25ClinicalIntradetrusor Botulinum Toxin A for OAB Via 1 Versus 10 Injections: A Randomized Clinical TrialResults posted
- 2026-02-01ClinicalProphylactic Analgesia in Outpatient Intradetrusor onabotulinumtoxinA Injections: Efficacy and Feasibility of Alternative Pain Control Methods in a Diverse Urban Patient PopulationWithdrawn
Therapeutic landscape
Therapies with a regulatory footing for this condition, alongside the wider set of agents co-studied with it in the literature.
Approval — Symptomatic treatment of urge incontinence and/or increased urinary frequency and urgency… (2004)
Approval — Symptomatic treatment of urge incontinence and/or increased urinary frequency and urgency… (2004)
Clinical trials
The current development programme across all trial phases.
Regulatory timeline
Drug regulatory events matched to this condition by indication — EMA.
European Medicines Agency (CC BY 4.0). Events are matched to this condition by drug indication text — approvals/updates for drugs indicated for it, not disease-specific acts.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes6
- Electric Stimulation Therapy1
- Urethra1
- Urinary Incontinence1
- Urinary Incontinence, Stress1
- Urinary Incontinence, Urge1
- Wireless Technology1
Leading journals1
- Nature communications1
Leading researchers8
- Gao Q1
- Kang N1
- Lee CHT1
- Liu M1
- Ma C1
- Shao L1
- Shao Y1
- Sitti M1
Affiliations (unnormalised)6
- Global College1
- Lee Kong Chian School of Medicine1
- Max Planck Institute for Intelligent Systems1
- Ruijin Hospital1
- School of Electrical and Electronic Engineering1
- School of Electrical Engineering1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Disease biology
Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.
Reference
Authoritative identity, definition & identifiers.
Involuntary discharge of URINE that is associated with an abrupt and strong desire to void. It is usually related to the involuntary contractions of the detrusor muscle of the bladder (detrusor hyperreflexia or detrusor instability).
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.