Disease

Ventricular Outflow Obstruction

Late-stage therapeutic developmentEmerging research

MeSHVentricular Outflow Obstruction

Publications

Clinical trials

2014

Latest publication

Latest activity

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Recent clinical, regulatory, research and industry developments relating to this disease.

2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy: the Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC).

Research2014-08-29European heart journal

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

1 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme

All trials

Active

Late-stage

Completed

Late-stage studies

Randomized Comparison of a Rivaroxaban-based Strategy With an Antiplatelet-based Strategy Following Successful TAVR for the Prevention of Leaflet Thickening and Reduced Leaflet Motion as Evaluated by Four-dimensional, Volume-rendered Computed Tomography (4DCT) - Substudy of the GALILEO-trial

Phase 3 · Completed · ECRI bv

Recently completed

Phase 3 · Completed · ECRI bv

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

European heart journal · 2014 · 2,990 cites

Recent publications

European heart journal · 2014 · 2,990 cites

Leading journals1

European heart journal1

Leading researchers8

Anastasakis A1
Borger MA1
Borggrefe M1
Cecchi F1
Charron P1
Elliott PM1
Hagege AA1
Lafont A1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Occlusion of the outflow tract in either the LEFT VENTRICLE or the RIGHT VENTRICLE of the heart. This may result from CONGENITAL HEART DEFECTS, predisposing heart diseases, complications of surgery, or HEART NEOPLASMS.

Identifiers

MeSHVentricular Outflow Obstruction

References & data sources

Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
Related entities are derived from literature co-mention (studied together) — associative, not causal.