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Disease

Wallerian Degeneration

Emerging researchRising momentum
3
Publications
1
Related conditions
2023
Latest publication
Latest activity
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Recent clinical, regulatory, research and industry developments relating to this disease.

NAD<sup>+</sup>, Axonal Maintenance, and Neurological Disease.

Research2023-09-07Antioxidants & redox signaling

Multiple sclerosis: an immune or neurodegenerative disorder?

Research2008-01-01Annual review of neuroscience

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Research activity

3 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20082023
Most influential

Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009 · 1,735 cites

Multiple sclerosis: an immune or neurodegenerative disorder?

Annual review of neuroscience · 2008 · 1,237 cites

NAD<sup>+</sup>, Axonal Maintenance, and Neurological Disease.

Antioxidants & redox signaling · 2023 · 16 cites
Recent publications

NAD<sup>+</sup>, Axonal Maintenance, and Neurological Disease.

Antioxidants & redox signaling · 2023 · 16 cites

Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009 · 1,735 cites

Multiple sclerosis: an immune or neurodegenerative disorder?

Annual review of neuroscience · 2008 · 1,237 cites
Major themes2
  • Neurodegenerative Diseases1
  • Peripheral Nervous System Diseases1
Leading journals3
  • Annual review of neuroscience1
  • Antioxidants & redox signaling1
  • The Journal of neuroscience : the official journal of the Society for Neuroscience1
Leading researchers8
  • Alexander JK1
  • Alexandris AS1
  • Ankeny DP1
  • Donnelly DJ1
  • Gensel JC1
  • Kigerl KA1
  • Koliatsos VE1
  • Nave KA1
Affiliations (unnormalised)4
  • and Johns Hopkins University School of Medicine1
  • Center for Brain and Spinal Cord Repair1
  • Johns Hopkins University School of Medicine1
  • Lerner Research Institute1

Related conditions

1 match

Diseases frequently studied alongside this one. Number shows shared papers.

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Degeneration of distal aspects of a nerve axon following injury to the cell body or proximal portion of the axon. The process is characterized by fragmentation of the axon and its MYELIN SHEATH.

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.