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Drug

1-Deoxynojirimycin

In clinical development
Emerging researchEarly-to-mid development
Also known as DNJ, Duvoglustat, D-1-deoxynojirimycin, Deoxynojirimycin+4 more

DNJ, Duvoglustat, D-1-deoxynojirimycin, Deoxynojirimycin, (+)-1-Deoxynojirimycin, 1 deoxynojirimycin, 1,5-dideoxy-1,5-imino-D-glucitol, 5-amino-1,5-dideoxy-D-glucopyranose.

1
Research papers

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
1-Deoxynojirimycin
Aliases & brands
DNJDuvoglustatD-1-deoxynojirimycinDeoxynojirimycin(+)-1-Deoxynojirimycin1 deoxynojirimycin1,5-dideoxy-1,5-imino-D-glucitol5-amino-1,5-dideoxy-D-glucopyranose
RxNorm CUI
43423
ChEMBL ID
CHEMBL307429
UNII
FZ56898FLE

Clinical trials

2 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
2
registered trials across all phases
LATEST COMPLETION 2013
1
Completed
1
Discontinued
PHASE DISTRIBUTIONn = 2
Phase 22

Recent completions

Trials that read out recently, adding to the completed evidence base.

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Major research themes2
Nervous System Diseases1Niemann-Pick Disease, Type C1
Journals, researchers & institutions
Top journals
  • Orphanet journal of rare diseases1
Leading researchers
  • Brassier A1
  • Broué P1
  • Cances C1
  • Chabrol B1
  • Dahmani-Rabehi B1
  • Eyer D1
  • Freihuber C1
  • Héron B1
Leading institutions
free-text, unnormalised
  • Department of Clinical Biochemistry1
  • Haguenau Hospital1
  • INSERM U1037 (Cancer Research Centre of Toulouse)1
  • Jean Verdier University Hospital1
  • Kremlin-Bicêtre University Hospital1
  • La Timone University Hospital1

Related drugs

1 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 2 of the same disease areas as 1-Deoxynojirimycin in the shared literature.

2 shared diseases1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials