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Drug

3-Hydroxybutyric Acid

In clinical development
Emerging researchEarly-to-mid developmentSteady momentum

Also known as Beta-Hydroxybutyrate, beta-Hydroxybutyric acid, 3-HYDROXY-BUTANOIC ACID.

4
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
3-Hydroxybutyric Acid
Aliases & brands
Beta-Hydroxybutyratebeta-Hydroxybutyric acid3-HYDROXY-BUTANOIC ACID
RxNorm CUI
2721211
ChEMBL ID
CHEMBL1162496
UNII
TZP1275679

Clinical trials

1 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
1
registered trials across all phases
LATEST COMPLETION 2022
1
Completed
PHASE DISTRIBUTIONn = 1
Phase 11

Recent completions

Trials that read out recently, adding to the completed evidence base.

Research activity

4 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20172024
Major research themes7
Diet, Ketogenic3Drug Resistance, Neoplasm1Epigenesis, Genetic1Gastrointestinal Microbiome1Immune Checkpoint Inhibitors1Prostatic Neoplasms1Signal Transduction1
Journals, researchers & institutions
Top journals
  • Annual review of nutrition1
  • Cancer research1
  • JCI insight1
  • Nutrients1
Leading researchers
  • Agostoni C1
  • Alves Costa Silva C1
  • Aprahamian F1
  • Arnedos M1
  • Asnicar F1
  • Colomba E1
  • Corsello A1
  • Daillère R1
Leading institutions
free-text, unnormalised
  • Aix Marseille Université1
  • Bambino Gesù Children Hospital1
  • Boler-Parseghian Center for Rare and Neglected Diseases1
  • Buck Institute for Research on Aging1
  • CNRS and Université Orléans1
  • Department of Clinical Sciences and Community Health1

Related drugs

3 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across the same disease area as 3-Hydroxybutyric Acid in the shared literature.

1 shared disease1 shared paper

Frequently co-studied with 3-Hydroxybutyric Acid in the research literature.

1 shared paper

Frequently co-studied with 3-Hydroxybutyric Acid in the research literature.

1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials