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Drug

Abatacept

Approved medicine
ResearchOngoing research

Also known as Orencia, Abatacept recombinant.

RxNorm614391UNII7D0YB67S97
2
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Immunogenicity of Biologics in Chronic Inflammatory Diseases: A Systematic Review.

Research2017-08-01Strand V · BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy

CTLA-4 is a second receptor for the B cell activation antigen B7.

Research1991-09-01Linsley PS · The Journal of experimental medicine

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Abatacept
Aliases & brands
OrenciaAbatacept recombinant
RxNorm CUI
614391
UNII
7D0YB67S97

Research activity

2 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
19912017
Most influential

CTLA-4 is a second receptor for the B cell activation antigen B7.

The Journal of experimental medicine · 1991 · 1,225 cites

Immunogenicity of Biologics in Chronic Inflammatory Diseases: A Systematic Review.

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2017 · 231 cites
Recent papers

Immunogenicity of Biologics in Chronic Inflammatory Diseases: A Systematic Review.

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2017 · 231 cites

CTLA-4 is a second receptor for the B cell activation antigen B7.

The Journal of experimental medicine · 1991 · 1,225 cites
Major research themes3
Immunoconjugates1Lymphocyte Activation1Receptors, Immunologic1
Journals, researchers & institutions
Top journals
  • BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy1
  • The Journal of experimental medicine1
Leading researchers
  • Al-Saleh J1
  • Balsa A1
  • Barile-Fabris L1
  • Brady W1
  • Damle NK1
  • Grosmaire LS1
  • Hawes C1
  • Horiuchi T1
Leading institutions
free-text, unnormalised
  • Bristol-Myers Squibb Pharmaceutical Research Institute1
  • Collegeville1
  • Dubai Hospital1
  • Hospital de Especialidades Centro Médico Nacional Siglo XXI1
  • Instituto de Investigación Sanitaria del Hospital Universitario La Paz (IdiPAZ)1
  • Keio University School of Medicine1

Related drugs

4 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 6 of the same disease areas as Abatacept in the shared literature.

6 shared diseases1 shared paper

Studied across 6 of the same disease areas as Abatacept in the shared literature.

6 shared diseases1 shared paper

Studied across 6 of the same disease areas as Abatacept in the shared literature.

6 shared diseases1 shared paper

Studied across 6 of the same disease areas as Abatacept in the shared literature.

6 shared diseases1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • Europe PMC — research literature