Back to discover
Drug

Antacids

In clinical development
Emerging researchLate-stage development

Also known as Antacid.

RxNorm863
1
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Interventional, Randomized, Open-Label, Crossover, Single-Dose, Relative Bioavailability Study Comparing Two Pharmaceutical Formulations of Lu AG06466 and Investigating the Food Effect on Lu AG06466 in Healthy Subjects

Clinical trial2021-12-29Completed · ClinicalTrials.gov

Pediatric Gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition.

Research2018-03-01Journal of pediatric gastroenterology and nutrition

A Phase 1, Open-Label, 3-Period Crossover Study Of The Effect Of An Antacid, A Proton Pump Inhibitor And An H2-Receptor Antagonist On Palbociclib (PD-0332991) Bioavailability Under Fed Conditions In Healthy Volunteers

Clinical trial2014-06-01Completed · ClinicalTrials.gov

A Randomized, Controlled Trial of Adding Intravenous Pantoprazole to Conventional Treatment for the Immediate Relief of Dyspeptic Pain

Clinical trial2013-09-18Results posted · ClinicalTrials.gov

Effect of Antacids on the Pharmacokinetics of Raltegravir in Healthy Volunteers

Clinical trial2009-12-01Completed · ClinicalTrials.gov

Effect of Antacids (Mg-Al-based) on Imatinib Mesylate (Gleevec®) Pharmacokinetics in Healthy Volunteers (CSTI571BUS257)

Clinical trial2008-10-01Completed · ClinicalTrials.gov

Single Dose Nexium 40MG QAM vs Lansoprazole 30mg BID for Control of Symptomatic GERD-A Double Blind Cross-Over Study

Clinical trial2007-12-01Completed · ClinicalTrials.gov

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Antacids
Aliases & brands
Antacid
RxNorm CUI
863

Clinical trials

6 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
6
registered trials across all phases
LATEST COMPLETION 2021
2
Late-stage (III+)
6
Completed
PHASE DISTRIBUTIONn = 6
Phase 14Phase 42

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

A Randomized, Controlled Trial of Adding Intravenous Pantoprazole to Conventional Treatment for the Immediate Relief of Dyspeptic Pain

CompletedPH IVChulalongkorn Universityn=872011

Single Dose Nexium 40MG QAM vs Lansoprazole 30mg BID for Control of Symptomatic GERD-A Double Blind Cross-Over Study

CompletedPH IVDigestive & Liver Disease Specialistsn=502007

Recent completions

Trials that read out recently, adding to the completed evidence base.

Interventional, Randomized, Open-Label, Crossover, Single-Dose, Relative Bioavailability Study Comparing Two Pharmaceutical Formulations of Lu AG06466 and Investigating the Food Effect on Lu AG06466 in Healthy Subjects

CompletedPH IH. Lundbeck A/Sn=162021

A Phase 1, Open-Label, 3-Period Crossover Study Of The Effect Of An Antacid, A Proton Pump Inhibitor And An H2-Receptor Antagonist On Palbociclib (PD-0332991) Bioavailability Under Fed Conditions In Healthy Volunteers

CompletedPH IPfizern=272014

A Randomized, Controlled Trial of Adding Intravenous Pantoprazole to Conventional Treatment for the Immediate Relief of Dyspeptic Pain

CompletedPH IVChulalongkorn Universityn=872011

Effect of Antacids on the Pharmacokinetics of Raltegravir in Healthy Volunteers

CompletedPH IUniversity of Colorado, Denvern=172009

Effect of Antacids (Mg-Al-based) on Imatinib Mesylate (Gleevec®) Pharmacokinetics in Healthy Volunteers (CSTI571BUS257)

CompletedPH IUniversity of Pittsburghn=122008

Single Dose Nexium 40MG QAM vs Lansoprazole 30mg BID for Control of Symptomatic GERD-A Double Blind Cross-Over Study

CompletedPH IVDigestive & Liver Disease Specialistsn=502007

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Journals, researchers & institutions
Top journals
  • Journal of pediatric gastroenterology and nutrition1
Leading researchers
  • Cabana M1
  • DiLorenzo C1
  • Gottrand F1
  • Gupta S1
  • Langendam M1
  • Rosen R1
  • Singendonk M1
  • Staiano A1
Leading institutions
free-text, unnormalised
  • Center for Motility and Functional Gastrointestinal Disorders1
  • Department of Clinical Epidemiology1
  • Emma Children's Hospital/AMC1
  • Great Ormond Street Hospital for Children1
  • Nationwide Children's Hospital1
  • University of California1
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials