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Drug

Aspartame

Research stage
Emerging research
Also known as 1-Methyl N-L-alpha-aspartyl-L-phenylalanate, 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester, 3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid, Asp-phe-ome+6 more

1-Methyl N-L-alpha-aspartyl-L-phenylalanate, 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester, 3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid, Asp-phe-ome, Aspartylphenylalanine methyl ester, L-Aspartyl-L-phenylalanine methyl ester, Aspartam, Aspartamine, Aspartamo, Aspartamum.

RxNorm1311524ChEMBLCHEMBL171679UNIIZ0H242BBR1
1
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Long-term metabolic effects of non-nutritive sweeteners.

Research2024-07-06Molecular metabolism

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Aspartame
Aliases & brands
1-Methyl N-L-alpha-aspartyl-L-phenylalanate3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acidAsp-phe-omeAspartylphenylalanine methyl esterL-Aspartyl-L-phenylalanine methyl esterAspartamAspartamineAspartamoAspartamum
RxNorm CUI
1311524
ChEMBL ID
CHEMBL171679
UNII
Z0H242BBR1

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Most influential

Long-term metabolic effects of non-nutritive sweeteners.

Molecular metabolism · 2024 · 12 cites
Recent papers

Long-term metabolic effects of non-nutritive sweeteners.

Molecular metabolism · 2024 · 12 cites
Major research themes2
Diet, High-Fat1Non-Nutritive Sweeteners1
Journals, researchers & institutions
Top journals
  • Molecular metabolism1
Leading researchers
  • Amir A1
  • Azem L1
  • Braun T1
  • Efroni G1
  • Haberman Y1
  • Hadar R1
  • Livne R1
  • Rathaus M1
Leading institutions
free-text, unnormalised
  • Sheba Medical Center1
  • The Dalia and David Arabov Endocrinology and Diabetes Research Center1

Related drugs

1 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Acetosulfame

Studied across 2 of the same disease areas as Aspartame in the shared literature.

2 shared diseases1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature