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Drug

Biotin

In clinical development
Emerging researchLate-stage development
Also known as Appearex, Coenzyme R, Concept OB, Dialyvite 800+19 more

Appearex, Coenzyme R, Concept OB, Dialyvite 800, Dialyvite 800 + Iron, Dialyvite 800 with Iron, Dialyvite 800 with Zinc, Hemax, Infuvite, Infuvite Pediatric, Irospan Tablet, Lexinal, Nephrocaps, Nephrocaps QT, Prenatal Rx 1, Vitabee with C, Vitamin B7, Vitamin H, Biotina, Biotine, Biotinum, cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid, cis-Tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.

1
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Can Biotin Supplementation be Used to Mask hCG Abuse?

Clinical trial2023-02-02Completed · ClinicalTrials.gov

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.

Research2009-07-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Biotin
Aliases & brands
AppearexCoenzyme RConcept OBDialyvite 800Dialyvite 800 + IronDialyvite 800 with IronDialyvite 800 with ZincHemaxInfuviteInfuvite PediatricIrospan TabletLexinalNephrocapsNephrocaps QTPrenatal Rx 1Vitabee with CVitamin B7Vitamin HBiotinaBiotineBiotinumcis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acidcis-Tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid
RxNorm CUI
1588
ChEMBL ID
CHEMBL857
ATC codes
A11HA05
UNII
6SO6U10H04

Clinical trials

3 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
3
registered trials across all phases
LATEST COMPLETION 2023
1
Late-stage (III+)
2
Completed
1
Discontinued
PHASE DISTRIBUTIONn = 3
Early Phase 11Phase 21Phase 31

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Recent completions

Trials that read out recently, adding to the completed evidence base.

Can Biotin Supplementation be Used to Mask hCG Abuse?

CompletedPH ISports Medicine Research and Testing Laboratoryn=102023

Safety and Tolerability of High Dose Biotin in Patients With Amyotrophic Lateral Sclerosis

CompletedPH IIAmerican University of Beirut Medical Centern=122021

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Most influential

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009 · 1,015 cites
Recent papers

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009 · 1,015 cites
Journals, researchers & institutions
Top journals
  • The Journal of neuroscience : the official journal of the Society for Neuroscience1
Leading researchers
  • Lee HG1
  • Li X1
  • Perry G1
  • Smith MA1
  • Su B1
  • Wang X1
  • Zhu X1
Leading institutions
free-text, unnormalised
  • Case Western Reserve University1
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials