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Drug

BMS-275183

Early clinical development
ClassTubulin stabiliser
15
Protein targets
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
BMS-275183
RxNorm CUI
320847
ChEMBL ID
CHEMBL4297268
UNII
UQC681JJIV
Primary mechanism
Tubulin stabiliser

Pharmacology & targets

15 targets

Known molecular targets and mechanisms supported by curated pharmacology databases.

Tubulin beta-4B chain
TUBB4B · P68371
STABILISERTubulin stabiliser
Tubulin beta-1 chain
TUBB1 · Q9H4B7
STABILISERTubulin stabiliser
Tubulin alpha-3C chain
TUBA3C · P0DPH7
STABILISERTubulin stabiliser
Tubulin alpha-4A chain
TUBA4A · P68366
STABILISERTubulin stabiliser
Tubulin beta-3 chain
TUBB3 · Q13509
STABILISERTubulin stabiliser
Tubulin alpha-1A chain
TUBA1A · Q71U36
STABILISERTubulin stabiliser
Tubulin beta-4A chain
TUBB4A · P04350
STABILISERTubulin stabiliser
Tubulin beta-8 chain
TUBB8 · Q3ZCM7
STABILISERTubulin stabiliser
Tubulin beta chain
TUBB · P07437
STABILISERTubulin stabiliser
Tubulin alpha-1B chain
TUBA1B · P68363
STABILISERTubulin stabiliser
Tubulin alpha-1C chain
TUBA1C · Q9BQE3
STABILISERTubulin stabiliser
Tubulin alpha-3E chain
TUBA3E · Q6PEY2
STABILISERTubulin stabiliser
Tubulin beta-2A chain
TUBB2A · Q13885
STABILISERTubulin stabiliser
Tubulin beta-2B chain
TUBB2B · Q9BVA1
STABILISERTubulin stabiliser
Tubulin beta-6 chain
TUBB6 · Q9BUF5
STABILISERTubulin stabiliser

Clinical trials

3 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
3
registered trials across all phases
3
Discontinued
PHASE DISTRIBUTIONn = 3
Phase 11Phase 22
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • ClinicalTrials.gov — clinical trials