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Drug

Carbimazole

Approved medicine
ClassThyroid peroxidase inhibitorResearchOngoing clinical research
Also known as Ethyl 3-methyl-2-thioimidazoline-1-carboxylate, Athyromazole, Carbethoxymethimazole, Carbimazol+3 more

Ethyl 3-methyl-2-thioimidazoline-1-carboxylate, Athyromazole, Carbethoxymethimazole, Carbimazol, Carbimazolo, Carbinazole, Carbimazolum.

Thyroid peroxidase
Primary target
2
Regulatory events
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Carbimazole
Aliases & brands
Ethyl 3-methyl-2-thioimidazoline-1-carboxylateAthyromazoleCarbethoxymethimazoleCarbimazolCarbimazoloCarbinazoleCarbimazolum
RxNorm CUI
2020
ChEMBL ID
CHEMBL508102
ATC codes
H03BB01
UNII
8KQ660G60G
Primary mechanism
Thyroid peroxidase inhibitor
Regulatory jurisdictions
mhra

Pharmacology & targets

1 target

Known molecular targets and mechanisms supported by curated pharmacology databases.

Thyroid peroxidase
TPO · P07202
INHIBITORThyroid peroxidase inhibitor

Regulatory timeline

2 events

The complete regulatory record, grouped by authority — approvals, safety advisories and label changes. Each authority shows its most recent events; expand one to read its full history.

Authorities
MHRA
Total events
2
mhraMedicines and Healthcare products Regulatory Agency· 2 events
2019-02-20Safety communicationSafety
Drug Safety Update: Carbimazole: risk of acute pancreatitis
Evidence ↗
2019-02-20Safety communicationSafety
Drug Safety Update: Carbimazole: increased risk of congenital malformations; strengthened advice on contraception
Evidence ↗

Contains public sector information from the Medicines and Healthcare products Regulatory Agency (MHRA) licensed under the Open Government Licence (OGL v3).

Clinical trials

1 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
1
registered trials across all phases
LATEST COMPLETION 2015
1
Late-stage (III+)
1
Completed
PHASE DISTRIBUTIONn = 1
Phase 31

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

CompletedPH IIINewcastle-upon-Tyne Hospitals NHS Trustn=812015

Recent completions

Trials that read out recently, adding to the completed evidence base.

CompletedPH IIINewcastle-upon-Tyne Hospitals NHS Trustn=812015
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • ClinicalTrials.gov — clinical trials
  • Regulatory event sources are credited in the Regulatory Timeline above.