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Drug

Carbon Monoxide

In clinical development
Emerging researchEarly-to-mid development

Also known as CO, Carboneum oxygenisatum, carbon(II) oxide.

2
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Effects of Carbon Monoxide Breathing on Blood Vessel Function

Clinical trial2019-03-01Completed · ClinicalTrials.gov

Carbon Monoxide Therapy for Severe Pulmonary Arterial Hypertension

Clinical trial2018-12-01Withdrawn · ClinicalTrials.gov

Gases as biological messengers: nitric oxide and carbon monoxide in the brain.

Research1994-09-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Carbon Monoxide
Aliases & brands
COCarboneum oxygenisatumcarbon(II) oxide
RxNorm CUI
2037
ChEMBL ID
CHEMBL1231840
ATC codes
V04CX08
UNII
7U1EE4V452

Clinical trials

4 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
4
registered trials across all phases
LATEST COMPLETION 2019
3
Completed
1
Discontinued
PHASE DISTRIBUTIONn = 4
Phase 12Phase 1 / 21Phase 21

Recent completions

Trials that read out recently, adding to the completed evidence base.

Effects of Carbon Monoxide Breathing on Blood Vessel Function

CompletedPH ICedars-Sinai Medical Centern=92019

Effects of Inhaled Carbon Monoxide on Pulmonary Inflammatory Responses Following Endotoxin Instillation

CompletedPH INational Institutes of Health Clinical Center (CC)n=352010

Modification of Chronic Inflammation by Inhaled Carbon Monoxide in Patients With Stable COPD

CompletedPH IIGroningen Research Institute for Asthma and COPDn=202006

Research activity

2 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
19942021
Most influential
Recent papers
Major research themes1
Second Messenger Systems1
Journals, researchers & institutions
Top journals
  • Scientific reports1
  • The Journal of neuroscience : the official journal of the Society for Neuroscience1
Leading researchers
  • Bečvář R1
  • Bubová K1
  • Dawson TM1
  • Distler JHW1
  • Heřmánková B1
  • Komarc M1
  • Oreská S1
  • Pavelka K1
Leading institutions
free-text, unnormalised
  • Charles University1
  • Department of Internal Medicine III and Institute for Clinical Immunology1
  • Institute of Rheumatology1
  • Johns Hopkins University School of Medicine1

Related drugs

2 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 3 of the same disease areas as Carbon Monoxide in the shared literature.

3 shared diseases1 shared paper

Frequently co-studied with Carbon Monoxide in the research literature.

1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials