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Drug

Cinacalcet

Regulatory activity · FDA
Emerging researchLate-stage development

Also known as CNC, N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine, Sensipar, Cinacalcet Hydrochloride.

2
Research papers
2
Active clinical trials
4
Regulatory events
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Recall (Class II): CINACALCET

Regulatory2026-06-29FDA

Recall (Class II): CINACALCET

Regulatory2026-06-29FDA

Recall (Class II): CINACALCET

Regulatory2026-06-29FDA

Novel Combination Therapy for Osteoporosis in Men

Clinical trial2025-06-30Primary completion · ClinicalTrials.gov

Recall (Class II): CINACALCET

Regulatory2024-11-07FDA

Evaluating Alternative Medical Therapies in Primary Hyperparathyroidism

Clinical trial2023-05-03Results posted · ClinicalTrials.gov

Renal Osteodystrophy: A Fresh Approach

Clinical trial2023-01-05Results posted · ClinicalTrials.gov

The OPTIMA study: assessing a new cinacalcet (Sensipar/Mimpara) treatment algorithm for secondary hyperparathyroidism.

Research2008-01-01Clinical journal of the American Society of Nephrology : CJASN

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Cinacalcet
Aliases & brands
CNCN-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amineSensiparCinacalcet Hydrochloride
RxNorm CUI
407990
ChEMBL ID
CHEMBL1201284
UNII
UAZ6V7728S
Regulatory jurisdictions
fda

Regulatory timeline

4 events

The complete regulatory record, grouped by authority — approvals, safety advisories and label changes. Each authority shows its most recent events; expand one to read its full history.

Authorities
FDA
Total events
4
fdaU.S. Food and Drug Administration· 4 events
2026-06-29RecallSafety
Recall (Class II): CINACALCET
Evidence ↗
2026-06-29RecallSafety
Recall (Class II): CINACALCET
Evidence ↗
2026-06-29RecallSafety
Recall (Class II): CINACALCET
Evidence ↗

Data from the U.S. Food and Drug Administration (U.S. Food and Drug Administration), public domain (CC0).

Clinical trials

47 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
47
registered trials across all phases
LATEST COMPLETION 2024
2
Active studies
1
Recruiting
35
Late-stage (III+)
39
Completed
6
Discontinued
PHASE DISTRIBUTIONn = 47
Phase 12Phase 210Phase 2 / 31Phase 311Phase 416Phase N / A7

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Recent completions

Trials that read out recently, adding to the completed evidence base.

Research activity

2 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20082009
Journals, researchers & institutions
Top journals
  • Clinical journal of the American Society of Nephrology : CJASN1
  • Nephron. Clinical practice1
Leading researchers
  • Bos WJ2
  • Bouman K2
  • Braun J2
  • Brink H2
  • Carter D2
  • Frazão JM2
  • Graf H2
  • Macário F2
Leading institutions
free-text, unnormalised
  • CROFF Policlinico di Milano1
  • Sheffield Kidney Institute1
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials
  • Regulatory event sources are credited in the Regulatory Timeline above.