Dalfampridine
Approved medicineAlso known as 4-AP, 4-Aminopyridine, 4-Pyridinamine, 4-Pyridylamine+7 more
4-AP, 4-Aminopyridine, 4-Pyridinamine, 4-Pyridylamine, 4AP, Ampyra, FAMPRIDINE, FAMPRIDINE (4-AMINOPYRIDINE), Fampridina, Fampridinum, p-Aminopyridine.
Recent clinical, regulatory, research and industry developments relating to this drug.
Supplemental approval: DALFAMPRIDINE (ANDA210158)
Effects of Twice-daily Dosing 4-AP on Functional Recovery After Spinal Cord Injury
4-Aminopyridine to Delay Carpal Tunnel Release or Resolve Carpal Tunnel Syndrome
4-aminopyridine Treatment for Nerve Injury Resulting From Radical Retro-Pubic Prostatectomy
4-aminopyridine for Skin Wound Healing
Label change: DALFAMPRIDINE (ANDA210158)
Label change: DALFAMPRIDINE (ANDA210158)
Label change: DALFAMPRIDINE (ANDA210158)
Profile
Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.
Pharmacology & targets
Known molecular targets and mechanisms supported by curated pharmacology databases.
Regulatory timeline
The complete regulatory record, grouped by authority — approvals, safety advisories and label changes. Each authority shows its most recent events; expand one to read its full history.
Data from the U.S. Food and Drug Administration (U.S. Food and Drug Administration), public domain (CC0).
Clinical trials
The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.
Late-stage studies
Phase III+ trials still open or recently active — where late-stage evidence is being generated.
Recent completions
Trials that read out recently, adding to the completed evidence base.
- RxNorm (U.S. National Library of Medicine) — drug identity
- ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
- ClinicalTrials.gov — clinical trials
- Regulatory event sources are credited in the Regulatory Timeline above.