Drug

Dexmedetomidine

In clinical development

Emerging researchLate-stage developmentRising momentum

Also known as Dexased, Dexdomitor, Dexmedesed, Dexmedvet+12 more

Dexased, Dexdomitor, Dexmedesed, Dexmedvet, Igalmi, Precedex, Sedexodine, Sileo, Dexmed-etomidine, Dexmedetomidin, Dexmedetomidina, Dextmedetomidine, dexemedetomidine, (+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole, Dexmedetomidine Hydrochloride, Dexmedetomidinum.

RxNorm48937 ChEMBLCHEMBL778UNII67VB76HONO

Research papers

Active clinical trials

Latest activity

beta

Recent clinical, regulatory, research and industry developments relating to this drug.

A Randomized Double-Blind Study Comparing the Effects of Preoperative Dexmedetomidine Versus Tramadol on Anxiety, Pain, and Hemodynamics in Patients Undergoing Hemorrhoidectomy

Clinical trial2026-07-28Status changed to Completed · ClinicalTrials.gov

Effect of Propofol, Midazolam, and Dexmedetomidine on Intracranial Pressure and Clinical Outcomes in Patients With Moderate-to-Severe Traumatic Brain Injury Undergoing Urgent Neurosurgical Intervention

Clinical trial2026-07-01Results expected Q2 2028 · ClinicalTrials.gov

Optimizing Patient-centred Outcomes Using Opioid Minimization Strategies (OPUS) Anesthesia: a Pilot Randomised Controlled Trial

Clinical trial2026-07-01Results expected Q2 2027 · ClinicalTrials.gov

The Application of Anesthesia Depth Monitoring on Post-operative Cognitive Dysfunction for Patients With Hydrocephalus Receiving Ventricular-peritoneal Shunt Surgery and Associated Change in CSF Metabolomics and Glymphatic Function.

Clinical trial2026-06-30Primary completion · ClinicalTrials.gov

A Phase 1b/2 Randomized, Double-Blind, Placebo-Controlled, Ascending-Dose Study of BXCL501 to Treat Symptoms of Acute Opioid Withdrawal in Patients With Opioid Use Disorder Who Are Physically Dependent on Opioids

Clinical trial2026-06-03Results posted · ClinicalTrials.gov

The Effects of Intrathecal Morphine in Addition to Serratus Anterior Plane Block and Dexmedetomidine on Postoperative Recovery (QoR-15) and Systemic Inflammation in Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial

Clinical trial2026-06-01Primary completion · ClinicalTrials.gov

Comparison of Intravenous Dexmedetomidine and Lignocaine in Reducing Hemodynamic Responses During Laryngoscopy and Endotracheal Intubation In Patients Undergoing Cardiac Surgery at Rawalpindi Institute Of Cardiology- A Randomized Controlled Trial

Clinical trial2026-05-28Results expected Q3 2026 · ClinicalTrials.gov

Pregabalin Versus Dexmedetomidine for Delirium Treatment After Coronary Artery Bypass Grafting: A Randomized Double-Blind Trial

Clinical trial2026-05-15Primary completion · ClinicalTrials.gov

Dexmedetomidine for treatment of hyperactive delirium in non-intubated ICU patients: the 4D randomized clinical trial.

Research2025-10-29Intensive care medicine

Optimization of Postoperative Intravenous Patient-Controlled Analgesia with Opioid-Dexmedetomidine Combinations: An Updated Meta-Analysis with Trial Sequential Analysis of Randomized Controlled Trials.

Research2017-11-01Pain physician

Efficacy and Safety of Dexmedetomidine as an Adjuvant in Epidural Analgesia and Anesthesia: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Research2017-04-01Clinical drug investigation

Pediatric Procedural Sedation Using Dexmedetomidine: A Report From the Pediatric Sedation Research Consortium.

Research2016-08-11Hospital pediatrics

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name

Dexmedetomidine

Aliases & brands

DexasedDexdomitorDexmedesedDexmedvetIgalmiPrecedexSedexodineSileoDexmed-etomidineDexmedetomidinDexmedetomidinaDextmedetomidinedexemedetomidine(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazoleDexmedetomidine HydrochlorideDexmedetomidinum

RxNorm CUI

48937

ChEMBL ID

CHEMBL778

UNII

67VB76HONO