Diphenhydramine
In clinical developmentAlso known as 2-(benzhydryloxy)-N,N-dimethylethylamine, 2-diphenylmethoxy-N,N-demthylethanamine, 40 Winks, Acetadryl+106 more
2-(benzhydryloxy)-N,N-dimethylethylamine, 2-diphenylmethoxy-N,N-demthylethanamine, 40 Winks, Acetadryl, Airacof, Aldex-CT, Aler-Dryl, Aleve PM, Allergia-C, Allermax, Altaryl, Antihist, Banophen, Banophen Cream, Beldin, Belix, Benadryl, Benadryl Allergy Plus Congestion, Benadryl Allergy Sinus, Benadryl Itch Stopping, Benadryl-D Allergy and Sinus, Benylin Multi-Symptom, Buckley's Bedtime Formula, Bydramine, Calagel, Calagel Reformulated Jun 2019, Compoz, Derma-Pax, Di-Delamine, Difenhidramina, Diphedryl, Diphenadryl, Diphendryl, Diphenhist, DiphenhydrAMINE Topical, Diphenyl, Diphenylin, Doans PM, Dormin, Dytan, Dytan-AT, Dytan-CD, Dytan-CS, Dytan-D, Dytan-HC, Dytuss, Endal CD, Endal HD, Excedrin PM, Excedrin PM Triple Action, Genahist, Genapap PM, HC-Derma-Pax, Hydramine, Kids-Eeze Allergy, Legatrin PM, Mapap PM, Masophen PM, Motrin PM, N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine, Nervine, Nu-Med, Nytol, O-benzhydryldimethylaminoethanol, Panadol PM, Pardryl, Pediaclear Cough, Percogesic Reformulated Jan 2011, QlearQuil Nighttime Allergy Relief, Rest Simply, Rindal HPD, Scot-Tussin Allergy, Siladryl, Simply Sleep, Sleep-Eze, Sleepinal, Sominex, Somnapure, Somnicaps, Tact, Tavist NightTime Allergy, The Itch Eraser, Tussinate, Tusstat, Twilite, Tylenol Cold Relief Nighttime Caplet, Tylenol PM, Uni-Hist, Unisom Sleep, Unisom with Pain Relief, Valu-Dryl, Vanamine, Vetadryl, Wal-Dryl, Wal-Dryl Allergy, Wal-Dryl Childrens, Wal-Dryl PE, Wal-Dryl-D, Wal-Sleep Z, Wal-Som, Wal-Som Maximum Strength, Z-Sleep, ZZZ Sleep, ZzzQuil, Dermamycin, Actifed Allergy Day/Night, Carbetapentane/Diphenhydramine/Phenylephrine, DiphenhydrAMINE Hydrochloride, Diphenhydramine-Zinc Acetate, Diphenhydraminum.
Recent clinical, regulatory, research and industry developments relating to this drug.
The Role of Histamines on Central Hemodynamics
Psilocybin-facilitated Treatment for Cocaine Use
Profile
Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.
Clinical trials
The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.
Late-stage studies
Phase III+ trials still open or recently active — where late-stage evidence is being generated.
Diphenhydramine as an Adjunct to Moderate Sedation for Procedural First Trimester Abortions
Recent completions
Trials that read out recently, adding to the completed evidence base.
Research activity
Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.
Major research themes2
Journals, researchers & institutions
- JAMA psychiatry1
- Baron T1
- Bhatt S1
- Bogenschutz MP1
- Forcehimes AA1
- Laska E1
- Mennenga SE1
- O'Donnell K1
- Owens LT1
- New York University Grossman School of Medicine1
- New York University Langone Center for Psychedelic Medicine1
- University of Alabama at Birmingham.1
- University of New Mexico Center on Alcohol1
- University of New Mexico School of Medicine1
Related drugs
Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).
Studied across the same disease area as Diphenhydramine in the shared literature.
- RxNorm (U.S. National Library of Medicine) — drug identity
- ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
- Europe PMC — research literature
- ClinicalTrials.gov — clinical trials