Drug

Fish Oils

In clinical development

Emerging researchLate-stage development

Also known as Fish oil containing omega-3 acids, Omega-3 Fish Oil, FISH OIL, Fishoil.

RxNorm4419UNII2SGI54470C

Research papers

Active clinical trials

Latest activity

beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients: a Phase II Multicenter Trial - A Randomized, Placebo-controlled Trial -

Clinical trial2026-07-08Results expected Q1 2030 · ClinicalTrials.gov

Millions take omega-3 fish oil for brain health but a new study found no benefit

Research2026-06-29Research news · Science Daily

Millions take omega-3 fish oil for brain health but a new study found no benefit

Research2026-06-29Research news · Science Daily

Investigating N-3 Fatty Acids to Prevent Neonatal Tobacco-related outcomeS

Clinical trial2026-06-04Results posted · ClinicalTrials.gov

Omega-3 fish oil shows promise against type 2 diabetes

Industry2026-05-31Science Daily

Fish oil may be hurting your brain, new study finds

Research2026-04-26Research news · Science Daily

Effects of Fish Oil and Red Wine on Oxidative Stress Biomarkers: a Randomized Double-blinded Trial on the Modulation of the Eicosanoid and Isoprostane Pathways in Healthy Subjects by Omega-3 Polyunsaturated Fatty Acids and Red Wine.

Clinical trial2026-02-24Results expected Q4 2028 · ClinicalTrials.gov

Omega-3 fish oil supplements could backfire without this key enzyme

Industry2026-02-13Science Daily

The Efficacy and Mechanisms of Action of n-3 Poly-unsaturated Fatty Acid Supplementation in People With Non-steroidal Exacerbated Airways Disease and Uncontrolled Asthma

Clinical trial2026-01-31Completed · ClinicalTrials.gov

Dietary Fish Oil and Metformin Intervention for Heart Health in PCOS

Clinical trial2025-12-12Results expected Q4 2026 · ClinicalTrials.gov

Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Knee Pain

Clinical trial2025-12-03Results posted · ClinicalTrials.gov

Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology?

Research2013-03-01British journal of clinical pharmacology

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name

Fish Oils

Aliases & brands

Fish oil containing omega-3 acidsOmega-3 Fish OilFISH OILFishoil

RxNorm CUI

4419

UNII

2SGI54470C

Clinical trials

36 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme

CLINICALTRIALS.GOV · LIVE REGISTRY

registered trials across all phases

LATEST COMPLETION 2026

Active studies

Recruiting

Late-stage (III+)

Completed

Discontinued

PHASE DISTRIBUTIONn = 36

Early Phase 11Phase 13Phase 29Phase 2 / 32Phase 34Phase 46Phase N / A11

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Fish Oil for Atrial Fibrillation - Effect and Mechanisms

CompletedPH IVVanderbilt Universityn=1902014

Use of Fish Oils to Prevent Atrial Mechanical Stunning and Atrial Remodeling Due to Atrial Arrhythmia

CompletedPH IVMelbourne Healthn=1002013

Use of Fish Oils to Reduce Recurrence of Atrial Fibrillation Following DC Cardioversion.

CompletedPH IVMelbourne Healthn=2002013

A Comparison Of The Effects Of Added Metformin (Versus No Added Metformin) On Psychopathology, Lipids, And Measures of Inflammation During The Initiation Or Re-Institution Of Treatment With Clozapine In Patients With Schizophrenia Or Schizoaffective Disorder

TerminatedPH IVDuke Universityn=342013

Use of Fish Oils to Reduce the Frequency and Duration of Episodes of Atrial Fibrillation in Patients With Paroxysmal Atrial Fibrillation.

CompletedPH IVMelbourne Healthn=802013

Recent completions

Trials that read out recently, adding to the completed evidence base.

The Efficacy and Mechanisms of Action of n-3 Poly-unsaturated Fatty Acid Supplementation in People With Non-steroidal Exacerbated Airways Disease and Uncontrolled Asthma

CompletedPH IIINorfolk and Norwich University Hospitals NHS Foundation Trustn=182026

Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Knee Pain

CompletedN/AKey trialBrigham and Women's Hospitaln=25,8712025

Investigating N-3 Fatty Acids to Prevent Neonatal Tobacco-related outcomeS

CompletedPH IIVanderbilt University Medical Centern=2372024

Efficacy of Fish Oil or Olive Oil Supplementation on the Health Effects of Ozone Exposure in Healthy Young Subjects

CompletedPH IUniversity of North Carolina, Chapel Hilln=442020

Dietary Fish Oil Intervention in Polycystic Ovary Syndrome

CompletedPH IUniversity of Albertan=522020

A Phase 0, Investigator Initiated Study, Evaluating the Impact of Omega 3 Fatty Acid Supplementation on Aromatase in Obese Postmenopausal Women With Estrogen Receptor Positive Breast Cancer

CompletedPH IThe University of Texas Health Science Center at San Antonion=242020

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Most influential

Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology?

British journal of clinical pharmacology · 2013 · 842 cites