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Drug

Granisetron

Approved · EMA
Late-stage development
Also known as Granisol, Kytril, Sancuso, Sustol+2 more

Granisol, Kytril, Sancuso, Sustol, Granisetron Hydrochloride, Granisetronum.

4
Active clinical trials
1
Regulatory events
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Drug Disposition and Nephrotoxicity

Clinical trial2025-08-11Results expected Q3 2027 · ClinicalTrials.gov

Approval: Sancuso (EMA)

Regulatory2012-04-20EMA

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Granisetron
Aliases & brands
GranisolKytrilSancusoSustolGranisetron HydrochlorideGranisetronum
RxNorm CUI
26237
ChEMBL ID
CHEMBL1290003
UNII
WZG3J2MCOL
Regulatory jurisdictions
ema

Regulatory timeline

1 event

The complete regulatory record, grouped by authority — approvals, safety advisories and label changes. Each authority shows its most recent events; expand one to read its full history.

Earliest approval
2012-04-20
Latest approval
2012-04-20
Authorities
EMA
Total events
1
emaEuropean Medicines Agency· 1 event
2012-04-20Approval
Approval: Sancuso (EMA)
Indication: Prevention of nausea and vomiting in patients receiving moderately or highly emetogenic chemotherapy, with or without cisplatin, for up to five consecutive days. Sancuso may beShow full indication

Prevention of nausea and vomiting in patients receiving moderately or highly emetogenic chemotherapy, with or without cisplatin, for up to five consecutive days. Sancuso may be used in patients receiving their first chemotherapy regimen or in patients who have previously received chemotherapy.

Evidence ↗

Contains information from the European Medicines Agency (European Medicines Agency), © EMA, reused under CC BY 4.0.

Clinical trials

68 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
68
registered trials across all phases
LATEST COMPLETION 2025
4
Active studies
2
Recruiting
41
Late-stage (III+)
47
Completed
17
Discontinued
PHASE DISTRIBUTIONn = 68
Phase 111Phase 1 / 21Phase 215Phase 2 / 31Phase 319Phase 412Phase N / A9

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Recent completions

Trials that read out recently, adding to the completed evidence base.

References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • ClinicalTrials.gov — clinical trials
  • Regulatory event sources are credited in the Regulatory Timeline above.