Drug

Inositol

In clinical development

Emerging researchLate-stage development

Also known as Amino-Cerv, Inositech, L-myo-Inositol, Pregnitude+4 more

Amino-Cerv, Inositech, L-myo-Inositol, Pregnitude, meso-Inositol, myo-inositol, 1,2,3,5/4,6-cyclohexanehexol, cis-1,2,3,5-trans-4,6-cyclohexanehexol.

RxNorm5833 ChEMBLCHEMBL1222251 ATCA11HA07UNII4L6452S749

Research papers

Active clinical trials

Latest activity

beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Comparison of Efficacy of Myo-Inositol Alone With Myo-Inositol Plus Alpha-Lactalbumin on Reproductive and Metabolic Parameters in Polycystic Ovarian Syndrome

Clinical trial2026-06-09Results expected Q2 2027 · ClinicalTrials.gov

A Randomized Controlled Trial Evaluating the Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol With or Without Metformin in Non-Diabetic Women With Polycystic Ovary Syndrome

Clinical trial2026-06-05Results expected Q3 2026 · ClinicalTrials.gov

Comparative Effectiveness of Metformin, Inositol, Dietary Restriction, and Combination Therapy in Polycystic Ovary Syndrome: A 12-Week Prospective Randomized Study

Clinical trial2026-01-13Completed · ClinicalTrials.gov

Inositol Supplementation to Treat Polycystic Ovary Syndrome: A Double Blind Dose Ranging RCT (INSUPP-PCOS)

Clinical trial2025-12-10Completed · ClinicalTrials.gov

Comparison of Myo-inositol Versus Metformin for Treating Obesity in Patients With Polycystic Ovarian Syndrome

Clinical trial2025-05-28Completed · ClinicalTrials.gov

Effect of Myo-Inositol- Based Co-treatment on Oocyte Quality in Women With Polycystic Ovarian Syndrome Undergoing Assisted Reproductive Technology

Clinical trial2023-12-01Primary completion · ClinicalTrials.gov

Effects of Myo-inositol on the Menstrual Cycle, Hyperandrogenism, Chronic Inflammatory Process and Carbohydrate Metabolism in Women With Polycystic Ovary Syndrome

Clinical trial2023-10-20Completed · ClinicalTrials.gov

Inositol for Comorbid Anxiety in Children and Adolescents With Bipolar Disorder

Clinical trial2023-10-04Withdrawn · ClinicalTrials.gov

The Effect of Myo-inositol, Somatropin, and DHEA on Poor Ovarian Responders Undergoing ICSI : an Open Label Randomized Clinical Trial.

Clinical trial2023-09-30Primary completion · ClinicalTrials.gov

The human milk component <i>myo</i>-inositol promotes neuronal connectivity.

Research2023-07-11Proceedings of the National Academy of Sciences of the United States of America

A Double-Blind, Placebo-Controlled Study of Inositol in Trichotillomania

Clinical trial2023-02-23Results posted · ClinicalTrials.gov

Myo-inositol for the Management of Poor Ovarian Responders: A Prospective Randomized Controlled Trial

Clinical trial2022-02-01Primary completion · ClinicalTrials.gov

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name

Inositol

Aliases & brands

Amino-CervInositechL-myo-InositolPregnitudemeso-Inositolmyo-inositol1,2,3,5/4,6-cyclohexanehexolcis-1,2,3,5-trans-4,6-cyclohexanehexol

RxNorm CUI

5833

ChEMBL ID

CHEMBL1222251

ATC codes

A11HA07

UNII

4L6452S749

Clinical trials

22 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme

CLINICALTRIALS.GOV · LIVE REGISTRY

registered trials across all phases

LATEST COMPLETION 2026

Active studies

Recruiting

Late-stage (III+)

Completed

Discontinued

PHASE DISTRIBUTIONn = 22

Early Phase 12Phase 1 / 22Phase 25Phase 2 / 32Phase 32Phase 43Phase N / A6

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Effect of Myo-Inositol- Based Co-treatment on Oocyte Quality in Women With Polycystic Ovarian Syndrome Undergoing Assisted Reproductive Technology

Unknown statusPH IVAmerican University of Beirut Medical Centern=1002023

Myo-inositol Versus Clomiphene Citrate as First Line Treatment for Ovulation Induction in PCOS

TerminatedPH IVUniversity Hospital, Ghentn=122022

A Randomized Controlled Trial of Inositol and Omega-3 Fatty Acids in Pediatric Mania

CompletedPH IVMassachusetts General Hospitaln=692019

A Randomized Controlled Trial Evaluating the Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol With or Without Metformin in Non-Diabetic Women With Polycystic Ovary Syndrome

RecruitingPH IIIBeni-Suef Universityn=1802026

The Effect of Myo-inositol, Somatropin, and DHEA on Poor Ovarian Responders Undergoing ICSI : an Open Label Randomized Clinical Trial.

Unknown statusPH II/IIIBeni-Suef Universityn=3002023

Recent completions

Trials that read out recently, adding to the completed evidence base.

Comparative Effectiveness of Metformin, Inositol, Dietary Restriction, and Combination Therapy in Polycystic Ovary Syndrome: A 12-Week Prospective Randomized Study

CompletedN/AIslamabad Medical and Dental Collegen=1922026

Inositol Supplementation to Treat Polycystic Ovary Syndrome: A Double Blind Dose Ranging RCT (INSUPP-PCOS)

CompletedPH IIMilton S. Hershey Medical Centern=1542025

Comparison of Myo-inositol Versus Metformin for Treating Obesity in Patients With Polycystic Ovarian Syndrome

CompletedN/AMuhammad Aamir Latifn=602025

Effects of Myo-inositol on the Menstrual Cycle, Hyperandrogenism, Chronic Inflammatory Process and Carbohydrate Metabolism in Women With Polycystic Ovary Syndrome

CompletedN/AUniversity of Sao Paulo General Hospitaln=602023

A Randomized Controlled Trial of Inositol and Omega-3 Fatty Acids in Pediatric Mania

CompletedPH IVMassachusetts General Hospitaln=692019

A Double-Blind, Placebo-Controlled Study of Inositol in Trichotillomania

CompletedPH IIUniversity of Chicagon=382016

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Most influential

The human milk component <i>myo</i>-inositol promotes neuronal connectivity.

Proceedings of the National Academy of Sciences of the United States of America · 2023 · 29 cites