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Drug

Ivermectin

Approved · FDA
Emerging researchLate-stage developmentRising momentum
Also known as Agrimectin, Bimectin, Bimectin Plus, DuraMectin+26 more

Agrimectin, Bimectin, Bimectin Plus, DuraMectin, Equimax, Heartgard Plus, Iverhart, Iverhart Plus, Ivermax, Ivermax Plus, Ivermectin Topical, Ivomec, Ivomec Plus, Noromectin, Noromectin Plus, Prazimectin, Privermectin, Promectin, Sklice, Soolantra, Strideguard, Stromectol, Tri-Heart Plus, Vetrimec, Vetrimec Plus, Zimecterin, Zimecterin Gold, Ivermectina, Ivermectine, Ivermectinum.

RxNorm6069UNII8883YP2R6D
4
Research papers
12
Active clinical trials
1
Regulatory events
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Tennessee pharmacies sell potent ivermectin, led by anti-vaccine doctor who’s taken ‘bucketloads’

Industry2026-06-19STAT News

Evaluation of the Impact of Oral Ivermectin (150 Micrograms/kg) on Musca Sorbens, the Putative Vector of Trachoma

Clinical trial2026-06-18Results expected Q4 2026 · ClinicalTrials.gov

Analysis of the Microbiome in Rosacea

Clinical trial2026-06-08Results expected Q3 2027 · ClinicalTrials.gov

Ivermectin Therapy for Scabies Infection in Children Younger Than 5 Years of Age (ITCHY Study)

Clinical trial2026-06-01Primary completion · ClinicalTrials.gov

A Phase I/II Study Evaluating the Safety and Efficacy of Ivermectin in Combination With Immune Checkpoint Inhibitor in Patients With Metastatic Triple Negative Breast Cancer

Clinical trial2026-05-06Results expected Q4 2026 · ClinicalTrials.gov

COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19)

Clinical trial2026-04-24Results posted · ClinicalTrials.gov

Approval: IVERMECTIN (ANDA218509)

Regulatory2026-04-07FDA

Epidermal Permeability Barrier Function and Stratum Corneum Hydration of Rosacea Following Application of Ivermectin

Clinical trial2026-03-27Results posted · ClinicalTrials.gov

The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro.

Research2020-04-03Antiviral research

The broad spectrum antiviral ivermectin targets the host nuclear transport importin α/β1 heterodimer.

Research2020-03-03Antiviral research

Efficacy and Safety of High-Dose Ivermectin for Reducing Malaria Transmission (IVERMAL): Protocol for a Double-Blind, Randomized, Placebo-Controlled, Dose-Finding Trial in Western Kenya.

Research2016-11-17JMIR research protocols

Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination.

Research2013-05-07Malaria journal

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Ivermectin
Aliases & brands
AgrimectinBimectinBimectin PlusDuraMectinEquimaxHeartgard PlusIverhartIverhart PlusIvermaxIvermax PlusIvermectin TopicalIvomecIvomec PlusNoromectinNoromectin PlusPrazimectinPrivermectinPromectinSkliceSoolantraStrideguardStromectolTri-Heart PlusVetrimecVetrimec PlusZimecterinZimecterin GoldIvermectinaIvermectineIvermectinum
RxNorm CUI
6069
UNII
8883YP2R6D
Regulatory jurisdictions
fda

Regulatory timeline

1 event

The complete regulatory record, grouped by authority — approvals, safety advisories and label changes. Each authority shows its most recent events; expand one to read its full history.

Earliest approval
2026-04-07
Latest approval
2026-04-07
Authorities
FDA
Total events
1
fdaU.S. Food and Drug Administration· 1 event
2026-04-07Approval
Approval: IVERMECTIN (ANDA218509)
Evidence ↗

Data from the U.S. Food and Drug Administration (U.S. Food and Drug Administration), public domain (CC0).

Clinical trials

123 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
123
registered trials across all phases
LATEST COMPLETION 2025
12
Active studies
8
Recruiting
73
Late-stage (III+)
77
Completed
34
Discontinued
PHASE DISTRIBUTIONn = 123
Early Phase 15Phase 111Phase 1 / 26Phase 228Phase 2 / 39Phase 335Phase 418Phase N / A11

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases: A Cluster-randomised Trial

RecruitingPH IVKey trialKirby Instituten=52,0002029

Evaluation of the Impact of Oral Ivermectin (150 Micrograms/kg) on Musca Sorbens, the Putative Vector of Trachoma

Not yet recruitingPH IVLondon School of Hygiene and Tropical Medicinen=122026

Comparison Effectiveness of Oral Ivermectin , 1% Permethrin Shampoo and 4% Dimeticone Liquid Gel in the Treatment of Pediculosis Capitis Among School Children in Chachoengsao Province, Thailand

Unknown statusPH IVPhramongkutklao College of Medicine and Hospitaln=1172024

Comparison of Effectiveness Between Three Dosages of Oral Ivermectin, Two Dosages of Oral Ivermectin, and Two Applications of Topical Permethrin In Scabies Patients

CompletedPH IVUniversitas Padjadjarann=602023

Ivermectin-artemisinin Combination Therapy for Eradication of Malaria

Unknown statusPH IVMakerere Universityn=1382022

Recent completions

Trials that read out recently, adding to the completed evidence base.

A Randomised, Double-blind, Placebo-controlled Trial to Assess the Safety, Pharmacokinetics, and Efficacy of Escalating Doses of Oral Ivermectin in Scabies Infected Children Weighing 5 to Less Than 15 Kilograms

CompletedPH IIUniversity of Oxfordn=2402025

Epidermal Permeability Barrier Function and Stratum Corneum Hydration of Rosacea Following Application of Ivermectin

CompletedPH IIWake Forest University Health Sciencesn=302025

Assessing Safety and Efficacy of Repurposed Oral Ivermectin in PKDL Treatment

CompletedPH IInternational Centre for Diarrhoeal Disease Research, Bangladeshn=302025

A Clinical Trial to Assess the Safety and Efficacy of Moxidectin Combination Treatments vs. Ivermectin Combination Treatments for Bancroftian Filariasis

CompletedPH IIIWashington University School of Medicinen=1642024

A Randomized, Double Blind, Parallel Group Clinical Trial to Evaluate the Safety of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas and in Individuals Living in Onchocerciasis Endemic Areas With High Levels of Lymphatic Filariasis Co-endemicity Receiving Concomitant Treatment With Albendazole

CompletedPH IIIKey trialMedicines Development for Global Healthn=12,9792024

Efficacy, Safety and Acceptability of Ascending Doses of Ivermectin in Combination With Albendazole for Trichuris Trichiura Infections in Preschool-aged Children: a Single-blind Randomised Controlled Dose-ranging Trial

CompletedPH IIJennifer Keisern=2602024

Research activity

4 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20132020
Major research themes1
Drug Approval1
Journals, researchers & institutions
Top journals
  • Antiviral research2
  • JMIR research protocols1
  • Malaria journal1
Leading researchers
  • Jans DA2
  • Abong'o B1
  • Aljayyoussi G1
  • Alonso P1
  • Atkinson SC1
  • Bassat Q1
  • Bayoh N1
  • Bogoyevitch MA1
Leading institutions
free-text, unnormalised
  • Biomedicine Discovery Institute1
  • Center for Global Health1
  • Centre for Global Health Research1
  • Liverpool School of Tropical Medicine (LSTM)1
  • Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology1
  • Nuclear Signalling Laboratory1
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials
  • Regulatory event sources are credited in the Regulatory Timeline above.