Drug

Nesiritide

In clinical development

Emerging researchLate-stage development

Also known as B-type natriuretic peptide, BNP, BNP-32, Brain natriuretic peptide+6 more

B-type natriuretic peptide, BNP, BNP-32, Brain natriuretic peptide, Brain natriuretic peptide 32, Human brain natriuretic factor-32, Natrecor, Natriuretic peptide B Type, Nesiritide (E. coli), nesiritide (hBNP).

RxNorm19666UNIIP7WI8UL647

Research papers

Active clinical trials

Latest activity

beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1

Clinical trial2024-12-01Terminated · ClinicalTrials.gov

A Randomized, Single-Blind, Placebo-Controlled, Single-Center Clinical Study of the Efficacy and Safety of Nesiritide on Early Postoperative Recovery After Total Cavo-Pulmonary Connection Surgery in Children

Clinical trial2020-07-01Primary completion · ClinicalTrials.gov

Specific Aims 3: Define in Hospitalized Decompensated CHF Patients With Renal Dysfunction, the Renal Actions of Low Dose Intravenous Infusion of BNP in the Presence and Absence of Acute PDE V Inhibition in Improving Renal Function

Clinical trial2019-12-01Completed · ClinicalTrials.gov

Therapeutic Effects of BNP in Hypertensive Patients

Clinical trial2018-12-01Primary completion · ClinicalTrials.gov

Septic cArdiac Deficiency and MenIngococcal seveRe Sepsis

Clinical trial2018-07-11Completed · ClinicalTrials.gov

To Define the Role of PDEV in Mediating the Decreased GFR and Attenuated Renal Sodium and cGMP Excretory Response to Acute Saline Volume Expansion in PSD and PDD With Renal Dysfunction.

Clinical trial2018-03-22Results posted · ClinicalTrials.gov

Assessing the Safety and Efficacy of Multifunctional Skin-adhesive Nanoparticles for UV Protection in Humans

Clinical trial2017-08-18Completed · ClinicalTrials.gov

BNP Pharmacodynamics and Effects on Metabolism in Lean and Obese Subjects

Clinical trial2017-02-28Completed · ClinicalTrials.gov

Natriuretic Peptides and Metabolic Risk in Obesity

Clinical trial2017-02-01Withdrawn · ClinicalTrials.gov

Modulation of novel cardiorenal and inflammatory biomarkers by intravenous nitroglycerin and nesiritide in acute decompensated heart failure: an exploratory study.

Research2011-05-16Circulation. Heart failure

Renal function and neurohormonal changes following intravenous infusions of nitroglycerin versus nesiritide in patients with acute decompensated heart failure.

Research2010-12-03Journal of cardiac failure

Sustained hemodynamic effects of an infusion of nesiritide (human b-type natriuretic peptide) in heart failure: a randomized, double-blind, placebo-controlled clinical trial. Natrecor Study Group.

Research1999-07-01Journal of the American College of Cardiology

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name

Nesiritide

Aliases & brands

B-type natriuretic peptideBNPBNP-32Brain natriuretic peptideBrain natriuretic peptide 32Human brain natriuretic factor-32NatrecorNatriuretic peptide B TypeNesiritide (E. coli)nesiritide (hBNP)

RxNorm CUI

19666

UNII

P7WI8UL647