Phenylephrine
In clinical developmentAlso known as AK-Dilate, AK-Nefrin, Afrin Nasal, Ah-Chew D+257 more
AK-Dilate, AK-Nefrin, Afrin Nasal, Ah-Chew D, Airacof, Ala-Hist AC, Alahist D, Aldex D, Aldex-CT, Atuss G, Atuss HD, Atuss MS, B-Tuss, Benadryl Allergy Plus Congestion, Benadryl-D Allergy and Sinus, Biorphen, Brompheniramine-Dextromethorph-Phenylephrine, Brompheniramine-Phenylephrine, Brovex PBC, C-Tanna 12D, Canges-HC, Carbatuss-CL, Carbetapentane-Phenylephrine, Chemdal HD, Chemdal HD Plus, Chemtussin HC, Chlopheniramine-Phenylephrine, Chlorgest HD, Chlorphen HD, Codimal DH, Codimal PH, Colrex, Comtussin HC, Crantex HC, Cyclomydril, Cyndal HD, Cytuss HC, Cytuss-HC NR, Dallergy, Dallergy Reformulated Nov 2011, De-Chlor G, De-Chlor HC, De-Chlor HD, De-Chlor MR, Demi-Cof, Despec-SF, Dexbrompheniramine-DM-Phenylephrine, Dicomal-DH, Dicomal-PH, Dimetapp Cold Drops, Ditussin-HC, Donatuss DC, Donatussin DC, Donatussin MAX, Dristan, DroTuss-CP, Duo-Medihaler, Duradal HD, Duradal HD Plus, Dynatuss HC, Dytan-CD, Dytan-CS, Dytan-D, Dytan-HC, Ear-gesic, Echotuss-HC, Ed-TLC, Ed-Tuss HC, Efasin-HD, Endagen-HD, Endal CD, Endal HD, Endal-HD Plus, Enditussin-HD, Endotuss-HD, Enplus-HD, Entex HC, Excof, Exetuss-HC, Exo-Tuss, Extendryl PEM, Fenilefrina, FluTuss HC, Formulation R, Gentex HC, Guiaphen HD, Guiaplex HC, H-C Tussive, H-C Tussive-NR, HYDROcodone CP, HYDROcodone HD, Hem-Prep, Hemorid, Hemorid Cream, Hemorid Ointment, Hemorrhoidal GRX, Hi-Tuss HC, Histinex HC, Histussin HC, Histussin-HC, Hyco-DH, Hycomal DH, Hycomine Compound, Hydro GP, Hydro-PC II, HydroFed, Hydron CP, Hydrophene DH, Hyphen-HD, Immphentiv, Iodal HD, Isopto Frin, K-Tan, KG-Dal HD, Levall 5.0, Liquicough HC, Little Noses Decongestant, Lortuss HC, Lusonal, M-End PE, M-Phen, Max HC, Maxi-Tuss HC, Maxi-Tuss SA, Maxiphen CD, Maxiphen CDX, Med-Hist-HC, Medicone Hemorrhoidal, Mintuss G, Mintuss HC, Mintuss MR, Mintuss MS, MonteFlu HC, Murocoll 2, Myci Spray, Mydcombi, Mydfrin, Nalex-DH, Nariz HC, Nasatuss, Nasop, Nasopen PE, Nasotuss, Nazarin HC, Neo-Synephrine, Notuss PD, Notuss-PE, Novahistine DH, Omidria, Otigesic, PCM, Pancof-PD, Pediacof, Pedituss, Phendal-HD, Phenergan VC, Phenergan VC with Codeine, Phenyl-T, Phenylephrine Nasal, Phenylephrine Ophthalmic, Phenylephrine, Topical, Phenylephrine-Tropicamide, Poly Hist DHC, Poly Hist Forte (old formulation), Poly Hist PD, Poly Hist PD (old formulation), Poly Tussin EX, Poly-Tussin AC, Poly-Tussin DHC, Prefrin, Prep-Hem, Prohist CD, Prohist LQ, Pyril D, Pyril Tann-12, Pyrlex PD, Q-Tuss with Hydrocodone, Qual-Tussin DC, Quindal HD, R(-)-Phenylephrine, RectiCare Advance Cream, Relacon-HC, Relasin-HC, Rhinall, Rindal HPD, Rindal-HD, Rolatuss, Rolatuss with Hydrocodone, Ru-Hist D, Ru-Hist-D, Ry-T-12, Ryna-12, S-T Forte, Simuc-HD, Statuss Green, Sudafed PE, Sudo-Tab, Sudogest PE, T- Koff, TL-Hist CD, Tannate 12D S, Tannihist-12D, Triant-HC, Trimal DH, Tusana-D, Tusdec-HC, Tuss-DS, Tuss-HC, Tuss-PD, Tussafed-HC, Tusscough DHC, Tussi-12D, Tussi-12D S, Tussinate, Tussirex, Tussive HC, Tussplex, Tympagesic, Uni Tuss HC, Uni-Lev 5.0, Uni-Tricof HC, Vanacof, Vanacof APE, Vanex-HD, Vasosulf, Vazculep, VazoTuss HC, Vazotab, Ventuss, Vetuss HC Syrup, Viravan-S, Viravan-T, Wal-Dryl PE, Wal-Dryl-D, Wal-Four, Wal-Phed PE, Xyralid, Z-Cof HC, Zincfrin, Zotex HC, Zotex-C, l-(3-Hydroxyphenyl)-N-methylethanolamine, Antipyrine/Benzocaine/Phenylephrine, Brompheniramine/Dihydrocodeine/PE, Carbetapentane/Diphenhydramine/Phenylephrine, Carbetapentane/Guaifenesin/Phenylephrine, Chlorpheniramine/Dextromethorphan/Phenylephrine, Chlorpheniramine/GuaiFENesin/Phenylephrine, Chlorpheniramine/Hydrocodone/Phenylephrine, Chlorpheniramine/Phenylephrin/Phenyltoloxamin, Chlorpheniramine/Phenylephrine/Pyrilamine, Dexbrompheniramine/Hydrocodone/Phenylephrine, Dexchlorpheniramine/Dextromethorphan/Phenylephrine, Dextromethorphan/Guaifenesin/Phenylephrine, Dextromethorphan/Phenylephrine/Pyrilamine, Guaifenesin/Hydrocodone/Phenylephrine, Guaifenesin/PE/PPA, Phenylephrine HCl, Phenylephrine Hydrochloride, Phenylephrinum, R-Tannic-S A/D.
Recent clinical, regulatory, research and industry developments relating to this drug.
Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity
Phenylephrine Tumescence for Hemostasis in Surgery for Burn Injury - A Randomized Control Trial
Clinical Study of DA-001 as a Treatment for Hair Shedding Reduction and Hair Re-Growth
Genetic variation in the alpha<sub>1B</sub>-adrenergic receptor and vascular response.
Genetic variation in the α1A-adrenergic receptor and phenylephrine-mediated venoconstriction.
Blacks have a greater sensitivity to α1-adrenoceptor-mediated venoconstriction compared with whites.
Profile
Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.
Clinical trials
The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.
Late-stage studies
Phase III+ trials still open or recently active — where late-stage evidence is being generated.
Sympathetic Neurovascular Transduction: Role of Adrenergic Receptors and Sex Differences
Recent completions
Trials that read out recently, adding to the completed evidence base.
Research activity
Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.
Major research themes2
Journals, researchers & institutions
- The pharmacogenomics journal2
- Hypertension (Dallas, Tex. : 1979)1
- Adefurin A3
- Ghimire LV3
- Kohli U3
- Kurnik D3
- Muszkat M3
- Paranjape SY3
- Sofowora GG3
- Stein CM3
- Division of Clinical Pharmacology3
- Center for Human Genetics Research2
- Clinical Pharmacology Unit1
- Technion-Israel Institute of Technology1
- Vanderbilt Genetics Institute1
- RxNorm (U.S. National Library of Medicine) — drug identity
- ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
- Europe PMC — research literature
- ClinicalTrials.gov — clinical trials