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Drug

Propionic acid

Research stage

Emerging research

Also known as Propanoic acid.

RxNorm34658 ChEMBLCHEMBL14021UNIIJHU490RVYR

2

Research papers

Latest activity

beta

Recent clinical, regulatory, research and industry developments relating to this drug.

The gut metabolite indole-3-propionic acid activates ERK1 to restore social function and hippocampal inhibitory synaptic transmission in a 16p11.2 microdeletion mouse model.

Research2024-03-28Microbiome

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.

Research2002-12-19The Journal of biological chemistry

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name

Propionic acid

Aliases & brands

Propanoic acid

RxNorm CUI

34658

ChEMBL ID

CHEMBL14021

UNII

JHU490RVYR

Research activity

2 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time

20032024

Most influential

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.

The Journal of biological chemistry · 2003 · 1,789 cites

The gut metabolite indole-3-propionic acid activates ERK1 to restore social function and hippocampal inhibitory synaptic transmission in a 16p11.2 microdeletion mouse model.

Microbiome · 2024 · 32 cites

Recent papers

The gut metabolite indole-3-propionic acid activates ERK1 to restore social function and hippocampal inhibitory synaptic transmission in a 16p11.2 microdeletion mouse model.

Microbiome · 2024 · 32 cites

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.

The Journal of biological chemistry · 2003 · 1,789 cites

Major research themes3

Autism Spectrum Disorder1Propionates1Receptors, G-Protein-Coupled1

Journals, researchers & institutions

Top journals

Microbiome1
The Journal of biological chemistry1

Leading researchers

Barnes AA1
Brown AJ1
Chang J1
Chang S1
Daniels D1
Dowell SJ1
Eilert MM1
Foord SM1

Leading institutions

free-text, unnormalised

Brain Research Centre1
Center for Advanced Biotechnology and Medicine1
China-UK Institute for Frontier Science1
Institute of Molecular Physiology1
Sun Yat-Sen Memorial Hospital1
The Afliated Hospital of Youjiang Medical University for Nationalities1

References & data sources

RxNorm (U.S. National Library of Medicine) — drug identity
ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
Europe PMC — research literature