Drug

Pyrrolidonecarboxylic Acid

In clinical development

Emerging researchLate-stage development

Also known as (-)-2-pyrrolidone-5-carboxylic acid, (S)-(-)-2-pyrrolidone-5-carboxylic acid, (S)-pyroglutamic acid, 5-L-oxoproline+11 more

(-)-2-pyrrolidone-5-carboxylic acid, (S)-(-)-2-pyrrolidone-5-carboxylic acid, (S)-pyroglutamic acid, 5-L-oxoproline, 5-Pyrrolidone-2-carboxylic acid, 5-oxo-2-pyrrolidinecarboxylic acid, 5-oxo-L-proline, Glutimic acid, L-5-Pyrrolidone-2-carboxylic acid, L-pyroglutamic acid, L-pyrrolidone carboxylic acid, PCA, PIDOLIC ACID, Pyroglutamic acid, PYRROLIDONE CARBOXYLIC ACID.

RxNorm9036 ChEMBLCHEMBL397976UNIISZB83O1W42

Research papers

Latest activity

beta

Recent clinical, regulatory, research and industry developments relating to this drug.

A Phase I Dose-escalation Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of a Single Administration of Extended-Release Injectable Suspension (ND-340) as Post-operative Analgesia in Patients With Total Knee Arthroplasty (TKA)

Clinical trial2026-06-01Suspended · ClinicalTrials.gov

Protein-responsive gut hormone tachykinin directs food choice and impacts lifespan.

Research2025-04-14Nature metabolism

Evaluating The Quality of Recovery After Elective Cesarean Section Using ObsQoR-10, A Comparative Study Between Two Modalities for Pain Control.

Clinical trial2024-05-30Completed · ClinicalTrials.gov

Effect of Tab Block and Patient Controlled Analgesia in Cesarean Section

Clinical trial2021-04-01Completed · ClinicalTrials.gov

Effect of Continue Rhomboid Intercostal and Subserratus Plane Block in Thorocotomy

Clinical trial2021-02-15Completed · ClinicalTrials.gov

The Effect Of Erector Spinae Plane Block On Postoperative Pain Management In Lumbar Disc Hernia Repair Operation

Clinical trial2020-02-04Completed · ClinicalTrials.gov

Efficacy of Regional Analgesia Techniques (Quadratus Lumborum Block and Transversus Abdominis Plane Block) in Acute and Chronic Pain Treatment in Patients After Cesarean Delivery

Clinical trial2019-08-30Completed · ClinicalTrials.gov

Effectiveness of Quadratus Lumborum Block After Nephrectomy

Clinical trial2019-08-25Completed · ClinicalTrials.gov

Patient Controlled Paravertebral Analgesia for Video-assisted Thoracoscopic Surgery

Clinical trial2017-07-01Completed · ClinicalTrials.gov

Randomized Controlled Trial Comparing Post-VATS Analgesia Between Patients With an Intrathecal Injection of Morphine and Sufentanil Versus Placebo.

Clinical trial2015-05-01Terminated · ClinicalTrials.gov

Effect of Thoracic Epidural Analgesia on Bowel Function Recovery in Major Upper Abdominal Surgeries

Clinical trial2015-03-01Completed · ClinicalTrials.gov

Hypokalemia and Intravenous Patient Controlled Analgesia

Clinical trial2010-12-01Completed · ClinicalTrials.gov

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name

Pyrrolidonecarboxylic Acid

Aliases & brands

(-)-2-pyrrolidone-5-carboxylic acid(S)-(-)-2-pyrrolidone-5-carboxylic acid(S)-pyroglutamic acid5-L-oxoproline5-Pyrrolidone-2-carboxylic acid5-oxo-2-pyrrolidinecarboxylic acid5-oxo-L-prolineGlutimic acidL-5-Pyrrolidone-2-carboxylic acidL-pyroglutamic acidL-pyrrolidone carboxylic acidPCAPIDOLIC ACIDPyroglutamic acidPYRROLIDONE CARBOXYLIC ACID

RxNorm CUI

9036

ChEMBL ID

CHEMBL397976

UNII

SZB83O1W42