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Drug

Pyruvic Acid

In clinical development
Emerging researchLate-stage developmentSteady momentum
Also known as 2-Oxopropansäure, 2-Oxopropionsäure, 2-ketopropionic acid, 2-oxopropanoic acid+7 more

2-Oxopropansäure, 2-Oxopropionsäure, 2-ketopropionic acid, 2-oxopropanoic acid, Acetylformic acid, BTS, Brenztraubensäure, Pyroracemic acid, a-Ketopropionic acid, acide pyruvique, alpha-ketopropionic acid.

RxNorm35161ChEMBLCHEMBL1162144UNII8558G7RUTR
4
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Pyruvic Acid
Aliases & brands
2-Oxopropansäure2-Oxopropionsäure2-ketopropionic acid2-oxopropanoic acidAcetylformic acidBTSBrenztraubensäurePyroracemic acida-Ketopropionic acidacide pyruviquealpha-ketopropionic acid
RxNorm CUI
35161
ChEMBL ID
CHEMBL1162144
UNII
8558G7RUTR

Clinical trials

1 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
1
registered trials across all phases
1
Late-stage (III+)
1
Discontinued
PHASE DISTRIBUTIONn = 1
Phase 2 / 31

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Comparison of 70% Pyruvic Acid Solution and Duofilm Solution in Treatment of Plantar Wart

Unknown statusPH II/IIIIsfahan University of Medical Sciencesn=602014

Research activity

4 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20122024
Major research themes4
Hippocampus1Mitochondria1Pyruvic Acid1Synaptic Transmission1
Journals, researchers & institutions
Top journals
  • Cell death & disease1
  • Molecular psychiatry1
  • Nature communications1
  • Science advances1
Leading researchers
  • Almustafa S1
  • Ashrafi G1
  • Baseler WA1
  • Cassel T1
  • Davies LC1
  • Fan TW1
  • Fiumelli H1
  • Frye RE1
Leading institutions
free-text, unnormalised
  • Center for Mass Spectrometry and Metabolic Tracing1
  • Department of Toxicology and Cancer Biology and Markey Cancer Center and Center for Environmental and Systems Biochemistry1
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development1
  • Imam Abdulrahman bin Faisal University1
  • International Child Development Resource Center1
  • Laboratory for Cellular Imaging and Energetics1

Related drugs

1 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Nitric Oxide

Studied across the same disease area as Pyruvic Acid in the shared literature.

1 shared disease1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials