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Drug

Rebimastat

Late-stage clinical development
ClassMatrix metalloproteinase 9 inhibitor
6
Protein targets
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Rebimastat
RxNorm CUI
620506
ChEMBL ID
CHEMBL76222
UNII
1B47R6ZX4K
Primary mechanism
Matrix metalloproteinase 9 inhibitor

Pharmacology & targets

6 targets

Known molecular targets and mechanisms supported by curated pharmacology databases.

INHIBITORMatrix metalloproteinase 9 inhibitor
INHIBITORMatrix metalloproteinase 8 inhibitor
Collagenase 3
MMP13 · P45452
INHIBITORMatrix metalloproteinase 13 inhibitor
INHIBITORMatrix metalloproteinase-1 inhibitor
INHIBITORMatrix metalloproteinase 14 inhibitor
INHIBITORMatrix metalloproteinase-2 inhibitor

Clinical trials

4 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
4
registered trials across all phases
LATEST COMPLETION 2009
1
Late-stage (III+)
4
Completed
PHASE DISTRIBUTIONn = 4
Phase 1 / 21Phase 22Phase 2 / 31

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Recent completions

Trials that read out recently, adding to the completed evidence base.

References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • ClinicalTrials.gov — clinical trials