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Drug

Rilpivirine hydrochloride

Established medicine
Also known as Complera, Edurant, Juluca, Odefsey+3 more

Complera, Edurant, Juluca, Odefsey, Rilpivirine, rilpivirine (as hydrochloride), rilpivirine HCl.

2
Regulatory events
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Rilpivirine hydrochloride
Aliases & brands
CompleraEdurantJulucaOdefseyRilpivirinerilpivirine (as hydrochloride)rilpivirine HCl
RxNorm CUI
1102287
Regulatory jurisdictions
emafda

Regulatory timeline

2 events

The complete regulatory record, grouped by authority — approvals, safety advisories and label changes. Each authority shows its most recent events; expand one to read its full history.

Earliest approval
2011-11-28
Latest approval
2026-07-10
Authorities
FDA · EMA
Total events
2
fdaU.S. Food and Drug Administration· 1 event
2026-07-10Approval
Approval: RILPIVIRINE HYDROCHLORIDE (ANDA219788)
Evidence ↗
emaEuropean Medicines Agency· 1 event
2011-11-28Approval
Approval: Edurant (EMA)
Indication: EDURANT, in combination with other antiretroviral medicinal products, is indicated for the treatment of human immunodeficiency virus type 1 (HIV 1) infection in paediatricShow full indication

EDURANT, in combination with other antiretroviral medicinal products, is indicated for the treatment of human immunodeficiency virus type 1 (HIV 1) infection in paediatric patients 2 to less than 18 years of age and weighing at least 14 kg to less than 25 kg without known mutations associated with resistance to the non-nucleoside reverse transcriptase inhibitor (NNRTI) class, and with a viral load ≤ 100,000 HIV 1 RNA copies/ml (see sections 4.4 and 5.1).Genotypic resistance testing should guide the use of EDURANT (see sections 4.4 and 5.1).EDURANT, in combination with other antiretroviral medicinal products, is indicated for the treatment of human immunodeficiency virus type 1 (HIV 1) infection in adults and paediatric patients weighing at least 25 kg without known mutations associated with resistance to the non-nucleoside reverse transcriptase inhibitor (NNRTI) class, and with a viral load ≤ 100,000 HIV 1 RNA copies/ml (see sections 4.4 and 5.1).Genotypic resistance testing should guide the use of EDURANT (see sections 4.4 and 5.1).

Evidence ↗

Data from the U.S. Food and Drug Administration (U.S. Food and Drug Administration), public domain (CC0).

Contains information from the European Medicines Agency (European Medicines Agency), © EMA, reused under CC BY 4.0.

References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • Regulatory event sources are credited in the Regulatory Timeline above.