Drug

Ropivacaine

In clinical development

Emerging researchLate-stage development

Also known as (S)-(-)-1-propyl-2',6'-pipecoloxylidide, (S)-ropivacaine, Naropin, Ropivacaina+4 more

(S)-(-)-1-propyl-2',6'-pipecoloxylidide, (S)-ropivacaine, Naropin, Ropivacaina, ropivicaine, L-N-n-propylpipecolic acid-2,6-xylidide, Ropivacaine Hydrochloride, Ropivacainum.

RxNorm35780 ChEMBLCHEMBL1077896UNII7IO5LYA57N

Research papers

Active clinical trials

Latest activity

beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Evaluation of Trigeminal Nerve Blockade in the Pterygopalatine Fossa for Cleft Palate Repair: a Pilot Study

Clinical trial2026-07-21Results expected Q2 2027 · ClinicalTrials.gov

Impact of Transversus Abdominis Plane Block Combined With Rectus Sheath Block on Postoperative Pain Management in Patients Undergoing Elective Robotic Colectomy

Clinical trial2026-06-03Results expected Q1 2028 · ClinicalTrials.gov

Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for PENG Block on Post Operative Pain Management in Patients Undergoing Hip Arthroplasty: a Prospective, Randomized, Single Blind, Active Controlled Study

Clinical trial2026-06-01Primary completion · ClinicalTrials.gov

The Addition of Dexmedetomidine to Ropivacaine in Bilateral Erector Spinae Plane Block in Patients Undergoing Coronary Artery Bypass Surgery - A Double-blinded Randomized Clinical Trial

Clinical trial2026-05-15Primary completion · ClinicalTrials.gov

Liposomal Bupivacaine Versus Ropivacaine for Preperitoneal Infiltration Analgesia in Upper Abdominal Laparotomy: A Randomized Double-Blind Controlled Trial

Clinical trial2026-05-01Primary completion · ClinicalTrials.gov

Post-operative Pain Control With Sphenopalantine Ganglion Nerve Block in Septorhinoplasty Patients

Clinical trial2026-04-27Results posted · ClinicalTrials.gov

A Multicenter, Randomized, Double-Blind, Active Drug and Placebo Parallel-Controlled, Dose-Escalation Phase I Study to Evaluate the Safety , Pharmacokinetics, and Efficacy of SYH9089 Injection in Patients Undergoing Abdominal Surgery

Clinical trial2026-04-09Results expected Q4 2026 · ClinicalTrials.gov

Erector Spinae Plane Block in Patients Undergoing Lumbar Spine Fusion Surgery: Iohexol Spread, Extent of Block and Efficacy

Clinical trial2026-03-11Results expected Q1 2027 · ClinicalTrials.gov

Liposomal Bupivacaine for Acute Pain Management Following Posterior Lumbar Decompression and Fusion Surgery in Adults: A Prospective, Randomized Controlled Trial

Clinical trial2026-03-03Completed · ClinicalTrials.gov

A Phase 2b, Randomized, Double-Blind, Saline Placebo- and Active-Controlled, Multicenter Study of HTX-011 Via Infiltration for Postoperative Analgesia in Subjects Undergoing Total Knee Arthroplasty

Clinical trial2026-03-02Results posted · ClinicalTrials.gov

Comparison of the Analgesic Efficacy between Levobupivacaine 0.25% and Ropivacaine 0.375% for PENG (Pericapsular Nerve Group) Block in the Context of Hip Fracture Surgery of Elderly Patients: A Single-Center, Randomized, and Controlled Clinical Trial.

Research2024-01-29Journal of clinical medicine

Effect of Stellate Ganglion Block Treatment on Posttraumatic Stress Disorder Symptoms: A Randomized Clinical Trial.

Research2020-02-01JAMA psychiatry

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name

Ropivacaine

Aliases & brands

(S)-(-)-1-propyl-2',6'-pipecoloxylidide(S)-ropivacaineNaropinRopivacainaropivicaineL-N-n-propylpipecolic acid-2,6-xylidideRopivacaine HydrochlorideRopivacainum

RxNorm CUI

35780

ChEMBL ID

CHEMBL1077896

UNII

7IO5LYA57N