Drug

Salsalate

In clinical development

Emerging researchLate-stage developmentSteady momentum

Also known as 2-Carboxyphenyl salicylate, Amigesic, Argesic-SA, Disalcid+17 more

2-Carboxyphenyl salicylate, Amigesic, Argesic-SA, Disalcid, Disalicylic acid, Disalicylsäure, Marthritic, Mono-Gesic, O-Salicylcylsalicylsäure, Salflex, Salicylic acid bimolecular ester, Salicyloxysalicylic acid, Salicyloylsalicylic acid, Salicylsalicylic acid, Salsitab, Sasapyrin, Sasapyrine, Sasapyrinum, o-Salicylsalicylic acid, Salsalato, Salsalatum.

RxNorm36108 ChEMBLCHEMBL154111UNIIV9MO595C9I

Research papers

Active clinical trials

Latest activity

beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use

Clinical trial2026-06-01Primary completion · ClinicalTrials.gov

Effects of Fish Oil ± Salsalate on the Omega-3 Index and the Circulating Lipodome of Omega-3 Polyunsaturated Fatty Acid Metabolites in Patients With Type 2 Diabetes and Diabetic Neuropathy

Clinical trial2026-04-06Results expected Q1 2027 · ClinicalTrials.gov

Treating Inflammation in Polycystic Ovary Syndrome to Ameliorate Ovarian Dysfunction

Clinical trial2025-06-10Results posted · ClinicalTrials.gov

Role of Angiotensin II and Chronic Inflammation in Persistent Microvascular Dysfunction Following Preeclamptic Pregnancy

Clinical trial2025-06-03Results posted · ClinicalTrials.gov

Targeting Inflammation With Salsalate in Type 1 Diabetes Neuropathy-TINSAL -T1DN

Clinical trial2025-05-16Results posted · ClinicalTrials.gov

Oral Peri-operative TIming of Metformin (or) Salsalate to Improve Non-cardiac Surgery Glucose Control - A Placebo-Controlled Internal Feasibility Trial

Clinical trial2024-12-01Withdrawn · ClinicalTrials.gov

Salsalate + Venetoclax/Decitabine for Patients With Acute Myelogenous Leukemia or Advanced Myelodysplasia/Myeloproliferative Disease

Clinical trial2023-05-24Results posted · ClinicalTrials.gov

A Phase 1b, 12-Month, Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of Salsalate in Patients With Mild to Moderate Alzheimer's Disease

Clinical trial2023-04-10Completed · ClinicalTrials.gov

Effect of Targeting Inflammation With Salsalate: The TINSAL-CVD Randomized Clinical Trial on Progression of Coronary Plaque in Overweight and Obese Patients Using Statins.

Research2016-07-01JAMA cardiology

Salicylate (salsalate) in patients with type 2 diabetes: a randomized trial.

Research2013-07-01Annals of internal medicine

A randomised trial of salsalate for insulin resistance and cardiovascular risk factors in persons with abnormal glucose tolerance.

Research2013-01-31Diabetologia

Salsalate is poorly tolerated and fails to improve endothelial function in virologically suppressed HIV-infected adults.

Research2010-07-01AIDS (London, England)

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name

Salsalate

Aliases & brands

2-Carboxyphenyl salicylateAmigesicArgesic-SADisalcidDisalicylic acidDisalicylsäureMarthriticMono-GesicO-SalicylcylsalicylsäureSalflexSalicylic acid bimolecular esterSalicyloxysalicylic acidSalicyloylsalicylic acidSalicylsalicylic acidSalsitabSasapyrinSasapyrineSasapyrinumo-Salicylsalicylic acidSalsalatoSalsalatum

RxNorm CUI

36108

ChEMBL ID

CHEMBL154111

UNII

V9MO595C9I