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Drug

Thymidine

In clinical development
Emerging researchEarly-to-mid development
Also known as 2'-deoxy-5-methyluridine, 2'-thymidine, 5-Methyl-2?-deoxyuridine, DEOXYRIBOTHYMIDINE+10 more

2'-deoxy-5-methyluridine, 2'-thymidine, 5-Methyl-2?-deoxyuridine, DEOXYRIBOTHYMIDINE, DOXRIBTIMINE, Deoxyribosylthymine, Kygevvi, MT-1621 COMPONENT 2'-DEOXYTHYMIDINE, Thymine 2'-deoxyriboside, Thymine deoxyriboside, dThd, 1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, 1-(2-Deoxy-?-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione, 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-?-D-erythro-pentofuranosyl)-5-methyl-.

1
Research papers
1
Active clinical trials
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Deoxythymidine and Deoxycytidine Treatment for Thymidine Kinase 2 (TK2) Deficiency

Clinical trial2026-01-28Results expected Q4 2026 · ClinicalTrials.gov

Regulation of adult neurogenesis by excitatory input and NMDA receptor activation in the dentate gyrus.

Research1995-06-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Thymidine
Aliases & brands
2'-deoxy-5-methyluridine2'-thymidine5-Methyl-2?-deoxyuridineDEOXYRIBOTHYMIDINEDOXRIBTIMINEDeoxyribosylthymineKygevviMT-1621 COMPONENT 2'-DEOXYTHYMIDINEThymine 2'-deoxyribosideThymine deoxyribosidedThd1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE1-(2-Deoxy-?-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-?-D-erythro-pentofuranosyl)-5-methyl-
RxNorm CUI
1372538
ChEMBL ID
CHEMBL52609
UNII
VC2W18DGKR

Clinical trials

2 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
2
registered trials across all phases
1
Active studies
1
Completed
PHASE DISTRIBUTIONn = 2
Phase 1 / 21Phase 21

Recent completions

Trials that read out recently, adding to the completed evidence base.

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Most influential

Regulation of adult neurogenesis by excitatory input and NMDA receptor activation in the dentate gyrus.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 1995 · 520 cites
Recent papers

Regulation of adult neurogenesis by excitatory input and NMDA receptor activation in the dentate gyrus.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 1995 · 520 cites
Major research themes1
Cell Division1
Journals, researchers & institutions
Top journals
  • The Journal of neuroscience : the official journal of the Society for Neuroscience1
Leading researchers
  • Cameron HA1
  • Gould E1
  • McEwen BS1
Leading institutions
free-text, unnormalised
  • Laboratory of Neuroendocrinology1
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials