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Drug

Toripalimab

Approved · EMA
Late-stage development
Also known as Loqtorzi, Teriplizumab, Teriprizumab, Terriptylimab+1 more

Loqtorzi, Teriplizumab, Teriprizumab, Terriptylimab, Triprolizumab.

RxNorm2669406UNII8JXN261VVA
117
Active clinical trials
1
Regulatory events
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

A Phase 1 Study of CHS-114 in Participants With Advanced Solid Tumors

Clinical trial2026-07-06Results expected Q3 2026 · ClinicalTrials.gov

Approval: Loqtorzi (EMA)

Regulatory2024-09-19EMA

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Toripalimab
Aliases & brands
LoqtorziTeriplizumabTeriprizumabTerriptylimabTriprolizumab
RxNorm CUI
2669406
UNII
8JXN261VVA
Regulatory jurisdictions
ema

Regulatory timeline

1 event

The complete regulatory record, grouped by authority — approvals, safety advisories and label changes. Each authority shows its most recent events; expand one to read its full history.

Earliest approval
2024-09-19
Latest approval
2024-09-19
Authorities
EMA
Total events
1
emaEuropean Medicines Agency· 1 event
2024-09-19Approval
Approval: Loqtorzi (EMA)
Indication: Loqtorzi, in combination with cisplatin and gemcitabine, is indicated for the first-line treatment of adult patients with recurrent, not amenable to surgery or radiotherapy, orShow full indication

Loqtorzi, in combination with cisplatin and gemcitabine, is indicated for the first-line treatment of adult patients with recurrent, not amenable to surgery or radiotherapy, or metastatic nasopharyngeal carcinoma. Loqtorzi, in combination with cisplatin and paclitaxel, is indicated for the first-line treatment of adult patients with unresectable advanced, recurrent, or metastatic oesophageal squamous cell carcinoma.

Evidence ↗

Contains information from the European Medicines Agency (European Medicines Agency), © EMA, reused under CC BY 4.0.

Clinical trials

198 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
198
registered trials across all phases
LATEST COMPLETION 2026
117
Active studies
104
Recruiting
30
Late-stage (III+)
14
Completed
67
Discontinued
PHASE DISTRIBUTIONn = 198
Early Phase 12Phase 116Phase 1 / 229Phase 2121Phase 2 / 37Phase 317Phase N / A6

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Recent completions

Trials that read out recently, adding to the completed evidence base.

References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ClinicalTrials.gov — clinical trials
  • Regulatory event sources are credited in the Regulatory Timeline above.