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Drug

Triamcinolone hexacetonide

In clinical development
Emerging researchLate-stage development

Also known as Hexatrione, Triamcinolone.

RxNorm38546
1
Research papers
9
Active clinical trials
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Prospective Randomized Controlled Clinical Trial: Superior Hypogastric Nerve Block for Pain Control After Uterine Artery Embolization: Effect of Addition of Steroids on Duration of Analgesia

Clinical trial2026-08-02Primary completion · ClinicalTrials.gov

Randomized Trial on the Evaluation of the Effectiveness of One Single Bone Marrow Aspirate Hip Injection Versus Triamcinolone for Hip Osteoarthritis

Clinical trial2026-06-11Results expected Q3 2027 · ClinicalTrials.gov

Utilization of a Cutaneous Therapy In Situ Microdevice

Clinical trial2026-06-03Results expected Q2 2030 · ClinicalTrials.gov

The TRIBECA Study (TRIessence/Byqlovi for Easier CAtaract Surgery)

Clinical trial2026-03-31Results expected Q4 2026 · ClinicalTrials.gov

Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study

Clinical trial2026-03-03Results expected Q1 2027 · ClinicalTrials.gov

A Phase 2b, Randomized, Double-masked, Multicenter, Dose-ranging, Sham-controlled Clinical Trial to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Clinical trial2026-02-23Completed · ClinicalTrials.gov

NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis: A Randomized, Controlled Trial

Clinical trial2026-02-23Results expected Q4 2026 · ClinicalTrials.gov

Triamcinolone With Vitamin D Synergistic Efficacy in Psoriasis

Clinical trial2026-02-19Results expected Q4 2026 · ClinicalTrials.gov

Multi-Center, Randomized Controlled Trial Evaluating the Effect of Adipose Tissue Processed With the SyntrFuge™ System for Knee Osteoarthritis

Clinical trial2025-12-01Primary completion · ClinicalTrials.gov

Clinical Outcomes of Conventional Versus Sidekick Cannulas in Lumbar Medial Branch Radiofrequency Ablation: A Prospective Randomized Study

Clinical trial2025-09-24Completed · ClinicalTrials.gov

A Comparative Study of Silver Nitrate, Triamcinolone, and Their Successive Combined Use on Hypergranulation Tissue in Traumatic Wounds: A Randomized Control Trial

Clinical trial2025-03-10Results expected Q4 2028 · ClinicalTrials.gov

Randomized trial of peribulbar triamcinolone acetonide with and without focal photocoagulation for mild diabetic macular edema: a pilot study.

Research2007-06-01Ophthalmology

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Triamcinolone hexacetonide
Aliases & brands
HexatrioneTriamcinolone
RxNorm CUI
38546

Clinical trials

90 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
90
registered trials across all phases
LATEST COMPLETION 2026
9
Active studies
8
Recruiting
72
Late-stage (III+)
51
Completed
30
Discontinued
PHASE DISTRIBUTIONn = 90
Early Phase 14Phase 12Phase 1 / 22Phase 210Phase 2 / 34Phase 311Phase 432Phase N / A25

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Utilization of a Cutaneous Therapy In Situ Microdevice

Not yet recruitingPH IVUniversity of California, San Franciscon=102030

The TRIBECA Study (TRIessence/Byqlovi for Easier CAtaract Surgery)

Not yet recruitingPH IVResearch Insight LLCn=402027

Evaluation of the Effect of Triamcinolone at Different Doses on Local Infiltration Anesthesia During Total Knee Arthroplasty

CompletedPH IVPeking University Third Hospitaln=1202024

Comparison of the Effectiveness of Ultrasound-Guided Perimeniscal Steroid and Dextrose Injections in Knee Osteoarthritis

CompletedPH IVKastamonu Universityn=312024

Suprascapular Nerve Block for Treatment of Shoulder Pain in Individuals With Spinal Cord Injuries

WithdrawnPH IVUniversity of Miami2024

Recent completions

Trials that read out recently, adding to the completed evidence base.

A Phase 2b, Randomized, Double-masked, Multicenter, Dose-ranging, Sham-controlled Clinical Trial to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

CompletedPH IIJanssen Research & Development, LLCn=3052026

Clinical Outcomes of Conventional Versus Sidekick Cannulas in Lumbar Medial Branch Radiofrequency Ablation: A Prospective Randomized Study

CompletedN/ASaglik Bilimleri Universitesi Gulhane Tip Fakultesin=822025

Evaluation of the Effect of Triamcinolone at Different Doses on Local Infiltration Anesthesia During Total Knee Arthroplasty

CompletedPH IVPeking University Third Hospitaln=1202024

Comparison of the Effectiveness of Ultrasound-Guided Perimeniscal Steroid and Dextrose Injections in Knee Osteoarthritis

CompletedPH IVKastamonu Universityn=312024

Percutaneous Trigger Finger Release Concomitant Steroid Injection Versus Percutaneous Trigger Finger Release Alone

CompletedPH IIIPolice General Hospital, Thailandn=382024

Effect of the Combination of Photobiomodulation Therapy and the Intralesional Administration of Corticoid in the Preoperative and Postoperative Periods of Keloid Surgery: a Randomized, Controlled, Double-blind Trial

CompletedN/AUniversity of Nove de Julhon=42023

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Journals, researchers & institutions
Top journals
  • Ophthalmology1
Leading researchers
  • Aiello LP1
  • Antoszyk A1
  • Beck R1
  • Bressler N1
  • Browning D1
  • Chew E1
  • Danis R1
  • Fan J1
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials