Back to discover
Drug

Tributyrin

In clinical development
Emerging researchLate-stage development

Also known as Glycerol Tributyrate.

1
Research papers
3
Active clinical trials
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Investigational Study of Glycerol Tributyrate in MELAS and LHON-Plus

Clinical trial2026-06-04Results expected Q1 2028 · ClinicalTrials.gov

Phase 2 Trial of Tributyrin in People With Parkinson's Disease and Cognitive Impairments

Clinical trial2025-11-12Results expected Q2 2027 · ClinicalTrials.gov

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Tributyrin
Aliases & brands
Glycerol Tributyrate
RxNorm CUI
38567
ChEMBL ID
CHEMBL118722
UNII
S05LZ624MF

Clinical trials

5 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
5
registered trials across all phases
LATEST COMPLETION 2003
3
Active studies
3
Recruiting
1
Late-stage (III+)
1
Completed
1
Discontinued
PHASE DISTRIBUTIONn = 5
Phase 12Phase 1 / 22Phase 31

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Recent completions

Trials that read out recently, adding to the completed evidence base.

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Major research themes4
Hippocampus1Memory, Short-Term1Neuronal Plasticity1Triglycerides1
Journals, researchers & institutions
Top journals
  • European journal of pharmacology1
Leading researchers
  • Del Olmo N1
  • Roca M1
  • Ruiz-Gayo M1
  • Sanz-Martos AB1
Leading institutions
free-text, unnormalised
  • School of Pharmacy1
  • School of Psychology1

Related drugs

1 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Frequently co-studied with Tributyrin in the research literature.

1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials