Drug

trichostatin A

In clinical development

Emerging researchEarly-to-mid development

Also known as TSA.

RxNorm2710658 ChEMBLCHEMBL99UNII3X2S926L3Z

Research papers

Active clinical trials

Latest activity

beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Tolerability Study of Trichostatin A In Subjects With Relapsed or Refractory Hematologic Malignancies

Clinical trial2026-03-16Results expected Q4 2027 · ClinicalTrials.gov

An Open Label Study to Investigate the Safety and Tolerability of Trichostatin A in Patients With Mild to Severe Onychomycosis

Clinical trial2026-02-04Results expected Q3 2026 · ClinicalTrials.gov

Intradermal Acupuncture Based on Changes in Biological Specificity of Acupoints for Major Depressive Disorder: a Prospective, Multicentre, Randomized, Controlled Trial

Clinical trial2023-12-31Completed · ClinicalTrials.gov

Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation.

Research2007-06-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood.

Research2006-02-16Proceedings of the National Academy of Sciences of the United States of America

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name

trichostatin A

Aliases & brands

TSA

RxNorm CUI

2710658

ChEMBL ID

CHEMBL99

UNII

3X2S926L3Z

Clinical trials

3 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme

CLINICALTRIALS.GOV · LIVE REGISTRY

registered trials across all phases

LATEST COMPLETION 2023

Active studies

Recruiting

Late-stage (III+)

Completed

PHASE DISTRIBUTIONn = 3

Phase 11Phase 21Phase N / A1

Recent completions

Trials that read out recently, adding to the completed evidence base.

Intradermal Acupuncture Based on Changes in Biological Specificity of Acupoints for Major Depressive Disorder: a Prospective, Multicentre, Randomized, Controlled Trial

CompletedN/AThe Third Affiliated hospital of Zhejiang Chinese Medical Universityn=1602023

Research activity

2 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time

20062007

Most influential

Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007 · 642 cites

Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood.

Proceedings of the National Academy of Sciences of the United States of America · 2006 · 516 cites