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Drug

Zinc Oxide

Regulatory activity · FDA
Emerging researchLate-stage developmentSteady momentum
Also known as A+D Diaper Rash, Ammens, Aquaphor Diaper Rash, Baby Anti Monkey Butt Diaper Rash Cream+68 more

A+D Diaper Rash, Ammens, Aquaphor Diaper Rash, Baby Anti Monkey Butt Diaper Rash Cream, Baby Butz Diaper Rash, Balmex, Baza Protect, Baza-Protect, Baza-Protect Reformulated June 2020, Booty Goo, CI 77947, Caldesene, Calmodrox, Calmol, Calmoseptine, Calprotect, Carlesta, Critic-Aid Skin, Delazinc, Dermagran BC, Desitin, Dr. Smith's Diaper Rash, Dr. Smith's Rash-N-All, Dynashield ZO, Flanders, Granulotion Medicated Lotion, Hemorid, Lantiseptic Multi-Purpose, Lassars Zinc, Little Bottoms Diaper Rash, Macuvite with Lutein, Manzatin-E, Medi-Paste, Menthol-Zinc Oxide, NicAzel, Nicomide, Nupercainal Suppository, Ocuvite, Ocuvite Lutein, PeriGuard, Prenatal Rx 1, PreserVision, PreserVision with Lutein, Rash Relief Antibacterial, Rash Relief Antifungal, Rash Relief with Zinc Oxide, Risamine, Sayman Salve, Seniortopix Healix, Soothe & Cool Skin Paste, Soothe and Cool Skin Paste, Triple Paste, Tronolane Anesthetic, Tronolane Suppositories, Tucks Hemorrhoidal, Unguentine Maximum Strength, Unna-Flex, Vitafol-One, Vusion, Welmedix Homecare Pro, Z-Bum, Z-Guard, ZINC (AS ZINC OXIDE), Zinc Oxide Paste, Zinc white, Zinci oxydum, Zincum oxydatum, oxyde de zinc, óxido de cinc, ZINC (AS OXIDE), Zinc óxido, Zinkoxid.

5
Research papers
1
Active clinical trials
1
Regulatory events
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Evaluation of Zinc Oxide Ointment in Treatment of Recurrent Aphthous Stomatitis

Clinical trial2026-03-30Completed · ClinicalTrials.gov

Recall (Class II): ZINC OXIDE

Regulatory2025-10-31FDA

Eco-friendly zinc oxide nanoparticle biosynthesis powered by probiotic bacteria.

Research2025-01-29Applied microbiology and biotechnology

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Zinc Oxide
Aliases & brands
A+D Diaper RashAmmensAquaphor Diaper RashBaby Anti Monkey Butt Diaper Rash CreamBaby Butz Diaper RashBalmexBaza ProtectBaza-ProtectBaza-Protect Reformulated June 2020Booty GooCI 77947CaldeseneCalmodroxCalmolCalmoseptineCalprotectCarlestaCritic-Aid SkinDelazincDermagran BCDesitinDr. Smith's Diaper RashDr. Smith's Rash-N-AllDynashield ZOFlandersGranulotion Medicated LotionHemoridLantiseptic Multi-PurposeLassars ZincLittle Bottoms Diaper RashMacuvite with LuteinManzatin-EMedi-PasteMenthol-Zinc OxideNicAzelNicomideNupercainal SuppositoryOcuviteOcuvite LuteinPeriGuardPrenatal Rx 1PreserVisionPreserVision with LuteinRash Relief AntibacterialRash Relief AntifungalRash Relief with Zinc OxideRisamineSayman SalveSeniortopix HealixSoothe & Cool Skin PasteSoothe and Cool Skin PasteTriple PasteTronolane AnestheticTronolane SuppositoriesTucks HemorrhoidalUnguentine Maximum StrengthUnna-FlexVitafol-OneVusionWelmedix Homecare ProZ-BumZ-GuardZINC (AS ZINC OXIDE)Zinc Oxide PasteZinc whiteZinci oxydumZincum oxydatumoxyde de zincóxido de cincZINC (AS OXIDE)Zinc óxidoZinkoxid
RxNorm CUI
11423
ChEMBL ID
CHEMBL3988900
UNII
SOI2LOH54Z
Regulatory jurisdictions
fda

Regulatory timeline

1 event

The complete regulatory record, grouped by authority — approvals, safety advisories and label changes. Each authority shows its most recent events; expand one to read its full history.

Authorities
FDA
Total events
1
fdaU.S. Food and Drug Administration· 1 event
2025-10-31RecallSafety
Recall (Class II): ZINC OXIDE
Evidence ↗

Data from the U.S. Food and Drug Administration (U.S. Food and Drug Administration), public domain (CC0).

Clinical trials

2 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
2
registered trials across all phases
LATEST COMPLETION 2026
1
Active studies
1
Recruiting
2
Late-stage (III+)
1
Completed
PHASE DISTRIBUTIONn = 2
Phase 42

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Recent completions

Trials that read out recently, adding to the completed evidence base.

Evaluation of Zinc Oxide Ointment in Treatment of Recurrent Aphthous Stomatitis

CompletedPH IVFaculty of Dental Medicine for Girlsn=1002026

Research activity

5 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20192026
Major research themes8
Nanoparticles3Zinc Oxide2Anti-Infective Agents1Bacteria1Mentha1Metal Nanoparticles1Nanowires1Photic Stimulation1
Journals, researchers & institutions
Top journals
  • Scientific reports2
  • Applied microbiology and biotechnology1
  • International journal of nanomedicine1
  • Science advances1
Leading researchers
  • Abbas M1
  • Abuçafy MP1
  • Ahmad N1
  • Al-Tameemi AI1
  • Ali A1
  • Ali S1
  • Aslam U1
  • Balamur R1
Leading institutions
free-text, unnormalised
  • Center for Biotechnology and Microbiology1
  • Centre of Plant Science and Biodiversity1
  • Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters1
  • College of Bioscience and Biotechnology1
  • College of Dentistry1
  • Dokuz Eylul University1

Related drugs

1 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Frequently co-studied with Zinc Oxide in the research literature.

1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials
  • Regulatory event sources are credited in the Regulatory Timeline above.