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ACKR3

Gene

atypical chemokine receptor 3

HGNCHGNC:23692EnsemblENSG00000144476NCBI Gene57007
Locus: gene with protein productLocation: 2q37.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCMKOR1 · CXCR7 · RDC1 · GPR159
View full nomenclature history (6)
Previous symbolsCMKOR1, CXCR7
Alias symbolsRDC1, GPR159
Previous nameschemokine orphan receptor 1, chemokine (C-X-C motif) receptor 7

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Pancreatic Neoplasms
Cutaneous melanoma
Colonic Neoplasms
Colorectal adenocarcinoma
Male reproductive organ cancer
Breast Neoplasms
Carcinoma, Hepatocellular
Lung carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Atypical chemokine receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-06-07.
Open TargetsGene–disease associations from the Open Targets Platform.