ACTG1

Gene

actin gamma 1

HGNCHGNC:144 EnsemblENSG00000184009 NCBI Gene71

Locus: gene with protein productLocation: 17q25.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asACTG · DFNA20 · DFNA26

View full nomenclature history (5)

Previous symbolsACTG, DFNA20, DFNA26

Previous namesdeafness, autosomal dominant 20, deafness, autosomal dominant 26

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neoplasms

Noonan syndrome

Cardiomyopathy, Hypertrophic

Costello syndrome

Neurodegenerative Diseases

Genetic Diseases, Inborn

Nonsyndromic genetic hearing loss

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Actins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.