ACVR1B

Gene

activin A receptor type 1B

HGNCHGNC:172 EnsemblENSG00000135503 NCBI Gene91

Locus: gene with protein productLocation: 12q13.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asACVRLK4 · ALK4 · SKR2 · ActRIB

View full nomenclature history (5)

Previous symbolsACVRLK4

Alias symbolsALK4, SKR2, ActRIB

Previous namesactivin A receptor, type IB

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Pancreatic adenocarcinoma

Colorectal adenocarcinoma

Carcinoma of liver and intrahepatic biliary tract

Carcinoma, Ductal, Breast

Adenocarcinoma of Lung

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Type 1 receptor serine/threonine kinases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.