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ACVRL1

Gene

activin A receptor like type 1

HGNCHGNC:175EnsemblENSG00000139567NCBI Gene94
Locus: gene with protein productLocation: 12q13.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asACVRLK1 · ORW2 · HHT2 · ALK1 · HHT
View full nomenclature history (8)
Previous symbolsACVRLK1, ORW2
Alias symbolsHHT2, ALK1, HHT
Previous namesactivin A receptor type II-like 1, activin A receptor type IL
Alias namesactivin receptor-like kinase 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Pulmonary arterial hypertension
Vascular Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Type 1 receptor serine/threonine kinases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.