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AFF4

Gene

ALF transcription elongation factor 4

HGNCHGNC:17869EnsemblENSG00000072364NCBI Gene27125
Locus: gene with protein productLocation: 5q31.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAF5Q31 · MCEF
View full nomenclature history (5)
Alias symbolsAF5Q31, MCEF
Previous namesAF4/FMR2 family, member 4, AF4/FMR2 family member 4
Alias namesALL1 fused gene from 5q31

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lung carcinoma
Carcinoma of liver and intrahepatic biliary tract
Carcinoma, Ductal, Breast

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

AF4/FMR2 familySuper elongation complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.