AGPAT1

Gene

1-acylglycerol-3-phosphate O-acyltransferase 1

HGNCHGNC:324 EnsemblENSG00000204310 NCBI Gene10554

Locus: gene with protein productLocation: 6p21.32

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLPAAT-alpha · LPLAT1

View full nomenclature history (6)

Alias symbolsLPAAT-alpha, LPLAT1

Previous names1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)

Alias nameslysophosphatidic acid acyltransferase, alpha, 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha, lysophospholipid acyltransferase l

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Infections

Autosomal dominant primary hypomagnesemia with hypocalciuria

Malignant hyperthermia of anesthesia

Nephrotic Syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

1-acylglycerol-3-phosphate O-acyltransferasesMicroRNA protein coding host genesLysophospholipid acyltransferases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.